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Showing 1 to 1 of 1 for “"BMP4/NOGGIN"”.
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NOGGIN Transport in a Model Human Epiblast
… Brivanlou/Siggia labs previously showed that (i) BMP4 initiates the cascade of events leading to gastrulation; (ii) BMP4 signal-reception is restricted to the basolateral domain; and (iii) in a human-specific manner, BMP4 directly induces the expression of NOGGIN. In this work, I interrogate the …