Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"BLNK"”.
-
Der inhibitorische Einfluss von CD22 auf das B-Zellrezeptorsignal nach Stimulation der B-Zelle
… BZR-Stimulation das Adaptermolekül SLP-65, auch BLNK oder BASH genannt, früher und stärker Tyrosin-phosphoryliert vorliegt, als in Kontroll-B-Zellen. Transfektionsexperimente mit der CD22-defizienten Plasmazytom-Zelllinie J558Lm3 wurden begonnen, um den molekularen Zusammenhang zwischen CD22, …
-
The Role of Foxo Transcription Factors in B Cell Development and Activation
… This is via activation of the PI3K/Btk/BLNK/PLC-gamma2 pathway. Conversely, Foxo mRNA expression is upregulated in immature B cells, both when the tonic/basal signal through the BCR is disrupted and when the BCR is engaged with anti-IgM. Overexpression of Foxo3 mRNA in an immature B cell …
-
Food processing modulation on breast cancer
… of tumor growth suppressing genes ATP2A3 and BLNK, and lower expression of oncogene MYC. Tumors in MI-fed mice expressed higher level of oncogene MYB and lower level of MHC-I and MHC-II, allowing tumor cells to escape immunosurveillance. MS-induced gene expression alterations were predictive …
-
Investigations on the role of SLP-65 and other B cell signaling proteins in human leukemia
SLP-65 is an adaptor protein preferentially expressed in B cells with a central role in BCR and pre-BCR mediated signal transduction. By providing multiple binding sites for other cellular effector molecules it assembles various proteins into one signaling complex. Therefore SLP-65 is involved in …