Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"BLM helicase"”.
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Npsd4: A New Player In Sumo-Dependent Dna Repair
… with and regulates the protein levels of BLM helicase, an important regulator</p> <p>of recombination which also can localize to PML NBs. The interaction of NPSD4 with BLM and the regulation of BLM levels by NPSD4 are SIM-dependent. Importantly, my work shows that the increased BLM levels …
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Mechanistic Understanding of the Role of TRF1 in Telomere Replication
… known. TRF1 functions in part by recruiting the BLM helicase, which can resolve G-quadruplexes on the lagging-strand template. Deletion of BLM leads to lagging strand specific fragile telomere formation. In this thesis, I report that analogous to CFSs, fragile telomeres in BLM-deficient cells …