Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 96 for “"BK"”.
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Role BK polyomaviru v lidských nádorech
BK polyomavirus (BKV) je malý neobalený ubikvitně rozšířený DNA virus, který u imunosuprimovaných jedinců může způsobovat závažná onemocnění, konkrétně BK polyomavirovou nefropatii (BKVaN) a hemoragickou cystitidu. Mimo toho se o BKV uvažuje jako o možném původci některých nádorových onemocnění u …
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Cloning of a putative human oncogenic virus, BK
… 1971, an immunologically distinct polyomavirus, BK, was isolated from the urine of an immunocompromised recipient of a renal allograft (Gardner et al., 1971). Interest in these two viruses in particular has been compounded by their potential oncogenicity in humans, (see section 1.8).
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Karo nusikaltimų traktuotė tarptautiniuose teisės aktuose ir LR BK /
This thesis provides a detailed analysis of the approach to war crimes in the instruments of the International law and in the Criminal code of the Republic of Lithuania. First of all, the conception of war crimes in international documents is analized, with an objective to provide a clear and …
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RCK Domain Model of Calcium Activation in BK Channels
… generation of action potentials in neurons. The BK channel family (BK for Big K<sup>+</sup> conductance) is an interesting subfamily of K<sup>+</sup> channels responsive to both membrane voltage and intracellular calcium ion. The unique, high-affinity Ca<sup>2+</sup> sensitivity of BK channels is …
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Monitoraggio del BK virus nei pazienti trapiantati di rene
Premessa: La nefropatia associata a BK virus (BKVAN) può essere diagnosticata solo mediante biopsia del graft renale. La mancanza di terapia efficace impone la diagnosi precoce dell'attivazione del virus BK, per prevenire la BKVAN nei pazienti nefro-trapiantati. La diagnosi precisa di BKVAN …
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An investigation into BK Polyomavirus and host-virus interactions
The potentially oncogenic human pathogen BK Polyomavirus (BKPyV) was first identified in 1971 and has since been associated with a number of diseases primarily in immunosuppressed patients. Infection is established in early life and by adulthood up to 90% of populations show seroconversion for the …
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Modulation of Cerebral Artery Smooth Muscle BK Channel Function by Neurosteroids
… Ca2+ activated K+ channels of large conductance (BK) channels are essential for many key physiological processes, such as controlling the contraction of smooth muscle, including cerebrovascular smooth muscle. Importantly, BK channels are made up of a homotetramer of α subunits which associate with …
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Protein Trafficking of BK Channel β1 Subunits in Cerebral Artery Myocytes
… (Ca<sup>2+</sup>)-activated potassium channels (BK) are expressed in arterial myocytes to control arterial contractility. It is composed of pore- forming BKα and auxiliary β1 subunits. Auxiliary β1 subunits associate with BKα which modulate Ca<sup>2+</sup> sensitivity of BK channel. Previous data …
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Genotypes and Clinical Characteristics of BK Virus in Kidney Transplant Recipients
PURPOSE: BK virus has emerged as a major cause of allograft loss in kidney transplant recipients over the past decade. The presence of BK virus in urine or blood indicates reactivation of the virus not necessarily accompanied by BK virus associated nephropathy. BK virus genotypes have been …
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Investigating the mechanisms of BK Polyomavirus egress and virus-host interactions.
BK polyomavirus (BKPyV) is a small, non-enveloped dsDNA virus that infects 70 – 90% of the world’s population and causes a lifelong, silently persistent infection. In immunocompromised individuals, BKPyV replication can result in serious pathology. Bone marrow transplant patients can develop …
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Neteisėto vertimosi ūkine, komercine, finansine ar profesine veikla (BK 202 str.) kvalifikavimo problemos /
Although the legislator's prerogative is to ensure clear and unambiguous regulation, the specifics of unauthorised engagement in economic activities raise fundamental qualification questions for the courts. Article 202 of the Criminal Code, which is the object of the master's thesis, is studied as …
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Acclimatization to High-Altitude, Long-Term Hypoxia Alters BK Channel Structure and Function
… possible mechanisms for the left shift of the BK channel I-V relationship in native basilar artery myocytes from the two LTH groups. These mechanisms included: differential expression of the accessary BK -1 subunit; differential phosphorylation of the BK subunit; and splice variation of the …
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Cholesterol Modulation of BK Currents and Cerebral Artery Diameter Via Channel-Forming Alpha-Subunit
… large conductance potassium channels (BK; MaxiK) are ubiquitously expressed and subsequently mediate numerous physiological processes. Cholesterol is consumed in high amounts with the diet and accumulates in cellular membranes when plasma levels become elevated. Cholesterol is a known …
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Molecular Mechanisms Underlying Alcohol-Induced Cerebral Artery Smooth Muscle BK Channel Inhibition and Eventual Cerebral Vasoconstriction
… calcium-and voltage-gated potassium (BK) channels. Indeed, ethanol (50 mM) decreases the steady-state activity (NPo) of vascular myocyte BK channels leading to an increase in cerebral artery tone. In native tissues, functional BK channels are oligomers of four channel-forming slo1 …
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The effect of single nucleotide polymorphisms and metabolic substrates on the cellular distribution of mammalian BK channels.
… channel, also known as the Big Potassium (BK) channel as an example, due to its ubiquitous expression and widespread varied role in human physiology, this study aimed to prioritise SNPs with the potential to affect the function of the channel. Using a BK channel resource created with …
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Regulation of Ca2+-Activated K+ Channel: Changes with Development
… change in response to iberiotoxin, a selective BK channel blocker, is significantly different between adult and fetal VSMCs. Our study of basilar VSMCs in whole-cell preparations showed that the total outward current density of fetal myocytes (57.9 ± 6.7 pA/pF) was greater than that of the adult …
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Role of Protein Kinase G in Regulating Vascular Tone in Hypoxic Ovine Cerebral Arteries
… of PKG involved with vasorelaxation is the BK channel alpha protein. To examine the influence of LTH on PKG-induced vasorelaxation, and to demonstrate the relative influence of the BK channel in these conditions, we used carotid and middle cerebral arteries from normoxic and chronically …
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Effet de la bradykinine sur la perméabilité des cellules endothéliales d'aorte bovine
… Nos résultats démontrent que la bradykinine (BK) produit une augmentation de la perméabilité endothéliale de l'ordre de 57% de la valeur basale à la concentration de 10-8M (p<0,01). De plus, l'effet concentration-dépendant de la BK est biphasique. Cette effet demeure lorsque la BK est …
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Evaluasi potensi limbah sabut siwalan terfermentasi EM-4 sebagai pakan sapi pedaging secara in-vitro
… EM-4 terhadap kandungan nutrisinya (BK, BO, PK, SK dan LK), kecernaan (BK dan BO), dan nilai total kecernaan (TDN) pada sapi secara in vitro. Penelitian ini bersifat eksperimental kuantitatif menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 3 ulangan. Perlakuan …
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