Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"BIOPHOTONICS"”.
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Nanofabrication towards biophotonics
This thesis explores methods for fabrication of nanohole arrays, and their integration into a benchtop system for use as sensors or anti-counterfeit labels. Chapter 1 gives an introduction to plasmonics and more specifically nanohole arrays and how they have potential as label free sensors compared …
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Electronic interfaces for biophotonics data capture
… an Analogue Front-End (AFE) interface for biophotonics data capture, featuring a Silicon Photomultiplier (SiPM) as the primary sensing component. The SiPM is uniquely suited for high-sensitivity, in-vivo cancer tumour detection biophotonics applications due to its high dynamic range, …
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Advanced fibre-based endoscopy for biophotonics applications
… turbidity restricts imaging, as well as other biophotonics techniques, to the most superficial layers of tissue.<br/><br/>A perspective strategy to overcome the turbidity of living matter exploits holographic light control in multimode optical fibres. This allows devising min-imally invasive …
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Diagnostic Neuropathology of Brain Tumours using Biophotonics and Spectrometry
Classification of tumours such as gliomas, which are on a continuous spectrum of histology and malignancy into distinct categories is still a challenge using histopathology. There has been significant advances in the techniques used to fight cancer in the past two decades. A number of studies have …
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Synthesis, Characterizations, And Evaluation Of New Reactive Two-photon Absorbing Dyes For Two-photon Excited Fluorescence Imaging Applications
… in the emergence of a novel area termed 'biophotonics'. The integrative and interdisciplinary nature of biophotonics cuts across virtually all disciplines, extending the frontiers of basic cellular, molecular, and biology research through the clinical and pharmaceutical industries. This …
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Three dimensional optofluidic devices for manipulation of particles and cells
… opportunities in fabricating novel devices for biophotonics applications. The work described in this thesis details the development of three dimensional optofluidic devices that can be used for biophotonics applications, in particular for performing cell manipulation and particle separation. …
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Focusing Light Inside Scattering Media with Optical Phase Conjugation
… is highly desired, and it could revolutionize biophotonics by enabling deep-tissue non-invasive high-resolution optical microscopy, optical tweezing, optogenetics, micro-surgery, and phototherapy.</p><p>To break the optical diffusion limit and focus light deep inside scattering media, optical …
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Advances in Stimulated Raman Scattering Microscopy via Deep Learning
… SRS microscopy has found an established niche in biophotonics with many examples of translational clinical applications and demonstrations of imaging various biological systems on subcellular to tissue spatial orders. Concurrent to the development of SRS microscopy, computational advancements have …
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Optical Printing of Multiscale Hydrogel Structures
… used for tissue engineering, lab on a chip and biophotonics applications. A range of optical fabrication technologies such as photolithography, digital projection stereolithography and laser direct writing have been used to shape hydrogels into structurally complex functional devices and …
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Advanced optical microscopy toolkits for non-invasive imaging in oncology
Despite significant advances in the fields of biophotonics and oncology alike, several challenges persist in the study, assessment, and treatment of cancer, ranging from the accurate identification and examination of potential risk factors, early diagnosis of dysplastic lesions, and monitoring of …
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Tissue Engineered Textiles: ‘Can the integration of textile craft with tissue-engineering techniques lead to the development of a new materiality for future design applications?’
… in collaboration with the Tissue Engineering & Biophotonics laboratory at Kings College London, the research has produced scaffolds that demonstrate how cells can use textiles as cues to orientate themselves, how to direct that orientation and how to selectively control growth. The original …
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Validation of photoacoustic imaging biomarkers in cancer biology
… current state-of-the art phantom materials in biophotonics are surveyed and general design considerations for preparation of tissue-mimicking phantoms are discussed to guide the development of a stable phantom material in PAI. Acoustic and optical material characterisation systems are then …
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Photophysics of Organic Probes and their Applications in Bioimaging & Photodynamic Therapy
… have been regarded as attractive tools in biophotonics. With the progress of ultrafast laser sources, two-photon absorption (2PA), in which a molecule absorbs two photons simultaneously, has opened possibilities of using it for various applications. Two-photon fluorescence microscopy …
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Upconverting nanoparticles: pushing theory and technology towards biomedical applications
Biophotonics faces a significant challenge in developing non-invasive imaging and interrogation techniques with high spatial resolution and penetration depth for precise diagnosis and treatment. These techniques rely on non-ionising radiation and non-toxic contrast agents possessing excellent photo …
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Novel Multifunctional Laser Diagnostics
The research presented in this thesis set out to contribute to knowledge seeking to advance the state-of-the-art in laser based, multi-functional, non-invasive diagnostic systems. The results of the work have contributed to the development of methodological generic approaches to the development of …
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Algorithmic techniques for manual-scanning and multi-sensory representation of optical coherence tomography data
Optical coherence tomography (OCT) is an emerging biomedical imaging modality that interferometrically measures the depth-resolved back-scattered light from a sample. The high resolution subsurface imaging capabilities of OCT can potentially provide valuable diagnostic feedback about tissue …
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Phantom and computational studies towards the clinical translation of gas in scattering media absorption spectroscopy into neonatal respiratory care
… of the work was done in a collaboration between Biophotonics@Tyndall, the Infant Centre (hosted at the Cork University Maternity Hospital-UCC) and the Swedish industry partner, GPX Medical who have built a pioneering GASMAS instrument, suitable for clinical use. The motivation behind this …
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Stimulated emission from biological materials and novel optical resonators for diagnostic and imaging applications
The first detailed optical characterization of any biological laser, providing spectral, temporal, threshold, and polarization characteristics for the flavin mononucleotide biomolecular laser, is presented here. In addition, our investigation of natural, bio-engineered, and complex biological laser …
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Single cancer cell detection with optofluidic intracavity spectroscopy
The detection of cancer cells is the basis for cancer diagnostics, cancer screening and cancer treatment monitoring. Non-destructive and non-chemical optical methods may help reduce the complexity and cost of related test, making them more available to the public. The label-free technique of …
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Label-free optical imaging of neural activity
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01
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