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Showing 1 to 20 of 32 for “"BH4"”.
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Vapor Pressures and Thermodynamic Properties of Mg(BH4)2, KBH4 and RbBH4 Using Torsion-Effusion and Thermogravimetric Method
… molecular weights of magnesium borohydride (Mg(BH4)2), potassium borohydride (KBH4) and rubidium borohydride (RbBH4). The torsion-effusion method was used to obtain the vapor pressures of effusing gases. The molecular weights of these gases were obtained by the gravimetric method which involved …
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The effects of tetrahydrobiopterin (BH4) treatement on nonverbal working memory-related brain activations and connectivity in individuals with phenylketonuria
… In many patients with PKU, tetrahydrobiopterin (BH4) treatment has been shown to reduce blood phe levels and, in some instances, to improve behavioral and cognitive symptoms associated with PKU. The present study sought to further examine the neurophysiological basis of nonverbal working memory …
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High coordination number compounds of thorium borohydride, and of calcium and strontium N,N-dimethylaminodiboranates
We have determined the crystal structure of Th(BH4)4 and confirmed that it is isomorphous with the tetragonal form of its uranium analogue. Of the four BH4- groups per formula unit, two are terminal and are bound to thorium in a tridentate κ3 fashion, and the other two BH4- groups bridge between …
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Role of BCL-XL in cell death after spinal cord injury
… (Tat-Bcl-xL), or to its anti-apoptotic domain BH4 (Tat-BH4). Intrathecal delivery of Tat-Bcl-xL, or Tat-BH4 for 24h or 7 days after SCI, resulted in a significant decrease in apoptosis at the site of injury. However, the 7 day delivery of Tat-Bcl-xL or Tat-BH4 impaired locomotor recovery beyond …
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Dispersion and Integration of Dopants by Mechanical Alloying in Complex Hydrogen Storage Materials
… dispersion. In the kinetically hindered Ca(BH4)2 system, initial efforts to synthesize Ca(BH4)2 from CaB 6 in this work were shown to be unsuccessful both structurally and microchemically by using a combination of energy dispersive spectroscopy, electron energy loss spectroscopy, and X-ray …
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The synthesis and application of tetrahydrobiopterin mimetics
… and other disease states. Tetrahydrobiopterin (BH4) is an important coenzyme for nitric oxide synthase and, without it, nitric oxide production halts. It is with this in mind that synthetic analogues of BH4 have been prepared and tested previously. This led to the discovery of a particularly …
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Dissecting the Roles of Cancer Cell Lipid Metabolism in Tumor Progression and Immune Evasion
… Our screens also identified tetrahydrobiopterin (BH4) biosynthesis as an essential metabolic pathway upon GPX4 inhibition. Mechanistically, BH4 is a potent radical-trapping antioxidant that protects lipid membranes from autoxidation, alone and in synergy with Vitamin-E. Dihydrofolate reductase …
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Characterization of a novel pro-apoptotic role for nuclear associated BCL-2
… Bcl-2 as a pro-apoptotic protein and Bcl-2’s BH4 domain as a critical domain for binding the chaperone protein FKBP38. Based on these findings we attempted a strategy for interfering with Bcl-2/FKBP38 binding via addition of a BH4 domain peptide both in vivo and in vitro. In both cases, …
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Transition Metal Hydroborate Complexes: Structures, Syntheses, and Use as Chemical Vapor Deposition Precursors
Passage of Zr(BH4)4 over heated substrates with a coincident flux of H atoms gives adhesive, mirror-bright films at a growth rate of 60 A/min. These films are smooth on the nanometer scale and possess electrical resistivities as low as 45 muO-cm. The films are free of carbon and have low …
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Modeling the Active Sites of [nickel-Iron]- and [iron-Iron]-Hydrogenases
… when treated with hydride sources such as BH4- or AlH4- at low temperature, generated the first terminal hydride-containing [FeFe]-hydrogenase model complex, [HFe2(S2C2H4)(mu-CO)(CO)(PMe 3)4]PF6. This complex readily protonates with strong acids in MeCN to evolve H2 and regenerate the …
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Modulating the Electrochemistry of Calcium Metal Anodes
… is proposed to govern electroactivity, the BH4 /Ca²⁺ ratio. Parasitic TFSI- decomposition prevents Ca plating when the BH4-/Ca²⁺ ratio is less than one. However, Ca plating in a TFSI--containing electrolyte is demonstrated for the first time when the BH4-/Ca²⁺ ratio is greater than 1, as …
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Beiträge zur Chemie von Hydroboraten BHnX4-n - (n = 1-4) des Lithiums, Natriums, Kaliums und Magnesiums
… Zusammensetzung der Verbindung im Vergleich zu LiBH4ž3 py (1) nicht. Das Tetrahydroborat zeigt m2- oder m3-Koordination zum Lithiumion. Bei einfacher ortho-Substitution der Pyridinringe wird eine Verbindung der Zusammensetzung (LiBH4ž2 L)2 erhalten, in der das Tetrahydroborat über ein 2m1 1, m1 …
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Volatile metal borohydride complexes: synthesis and characterization of new chemical vapor deposition precursors
… N,N-dimethylimine and magnesium borohydride, Mg(BH4)4, were observed by 11B NMR in the reaction mixture. Static chemical vapor deposition (CVD) has been successfully used to deposit conformal thin films of hafnium diboride, HfB2, and iron metal from hafnium borohydride, Hf(BH4)4, and iron …
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Synthesis and indentation of boride and carbide coated carbon nanotube composite microstructures
… static CVD with a hafnium diboride precursor (Hf[BH4]4) leading to coating thicknesses ranging from 3nm to 50 nm; and (ii) through cycles of elasto-capillary imbibition and pyrolysis of a silicon oxycarbide (SiOC) polymer derived ceramic leading to coating thickness from 8 nm to full infiltration. …
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The role of Zinc and Reactive Oxygen Species in the Regulation of Endothelial Nitric Oxide Synthase
… an eNOS enzyme cofactor, tetrahydrobiopterin (BH4), was found to help maintain eNOS protein due to its high antioxidant potential. In conclusion, eNOS appears to be regulated by NO and ROS through an increase in intracellular Zn, thus activating MTF-1, which binds to the 5' flanking region of …
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The role of Zinc and Reactive Oxygen Species in the Regulation of Endothelial Nitric Oxide Synthase
… an eNOS enzyme cofactor, tetrahydrobiopterin (BH4), was found to help maintain eNOS protein due to its high antioxidant potential. In conclusion, eNOS appears to be regulated by NO and ROS through an increase in intracellular Zn, thus activating MTF-1, which binds to the 5' flanking region of …
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Chemistry of B1- and B10- boranes containing halogen or pseudohalogen groups
… routes to amine-boranes and -cyanoboranes from [BH4]- and [BH3CN]- substrates. This chapter discusses some difficulties encountered when polyamines were used in these reactions. The characterisation of an unusual ketone isolated from some of these reactions, the X-ray crystallographically …
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THE INTERPLAY BETWEEN ESTROGENS AND THE NITRIC OXIDE SYSTEM IN CARDIAC FUNCTION AND STRUCTURE
It is increasingly recognized that biological differences in the mechanisms regulating cardiovascular function in women and men critically impact the expression, clinical presentation, and outcomes of chronic diseases such as hypertension, diabetes, and heart failure. This is borne out from …
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Developing Core-Shell Borohydride Nanoarchitectures and Understanding their Structure-Hydrogen Release/Uptake Relationships
… (i) understand the paths to synthesise various NaBH4 nanoarchitectures (e.g. spheres, cubes, or bars) and potential nanostructure/H2 property interdependencies, (ii) rationalise the fabrication of core-shell NaBH4@Ni using wet-chemistry approaches to confine NaBH4 for reversible H2 storage, (iii) …
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