Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"BFA"”.
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Eine Untersuchung zur Endozytose in Pflanzenzellen
… membrane and assess the effect of Brefeldin A (BFA) on both pathways in plant cells. BFA is a fungal toxin and affects Golgi structure, endocytic recycling and secretion in animal cells. Imaging of the BFA effects in the cellular context in plant cells showed the formation of ER-Golgi hybrids …
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The Development of an Economic Feasibility Decision Support System for a Building Automation and Control System
… Feasibility Assessment Decision Support System (BFA DSS)—a proof-of-concept model class DSS tool, designed to estimate the financial and energy feasibility of BACS installations within the South African environment for lecture halls and office block buildings. The research thereby contributes to …
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Strukturelle Untersuchungen zur Inhibierung und Biogenese des pflanzlichen Golgi-Apparates
… Voruntersuchungen behandelten die Wirkungen von BFA auf unterschiedliche Phasen des Zellzykluses. Zugabe von Brefeldin A während der Zellteilung von BY2 Zellen hatte demnach nicht nur Einfluss auf die Cytokinese, es konnten auch Beeinträchtigungen der Karyogenese festgestellt werden. Mitotischen …
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Cellular Trafficking and Processing Pathways of the Alzheimer β/A4 Amyloid Precursor Protein
… Treatment with either monensin or brefeldin A (BFA) prevented normal APP maturation (N- and O-glycosylation and tyrosine sulfation) and abolished APP secretion. Phorbol ester produced a several-fold increase in APP secretion, indicating that protein phosphorylation regulates intra-β/A4 amyloid …
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Role of O-GlcNAc in the Vertebrate Secretory Pathway
… workflow we examined the effects of brefeldin A (BFA), a fungal metabolite that disrupts vesicle trafficking, and cytokine deprivation on a pro-B cell line. We identified changes in the O-GlcNAcylation of Coatomer subunit gamma-1 (COPG) a coat protein complex I (COPI) component in response to BFA. …
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Employment opportunities in the South African hotel industry with special reference to tourism
… Services and the Bureau of Financial Analysis (BFA) of the University of Pretoria were used. The 1982 Manpower Survey of the BFA proved particularly useful in establishing the present distribution of skilled staff in the industry by hotel grading and by geographical area. Performance ratios were …
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Biomechanical and histological evaluation of a new zirconia implant in a canine model
… apposition rate (MAR), bone forming area (BFA), and Periotest value (PTV) of the two groups were studied and compared. Results: At 12 weeks post operatively, one Shofu thread type Ti implant were not integrated. Over all failure implant was 0/12 in zirconia group, and 1/12 in titanium …
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Machine learning for corporate failure prediction : an empirical study of South African companies
… each company. Such data was mainly sourced from BFA McGregor RAID Station, although the BFA McGregor Handbook and JSE Handbook were also consulted for certain data items. A total of 75 financial and non-financial ratios were calculated for each year of data collected for every company in the …
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Grey matter morphological changes in late life using magnetic resonance imaging technique
… of the ageing brain. The basal forebrain area (BFA) is closely connected to the hippocampus by virtue of cholinergic neuronal projections. Structural neuroimaging studies have shown reduced volumes of both structures in mild cognitive impairment (MCI); however, of interest is the understanding …
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Secretion and delivery of virulence proteins from <i>Phytophthora infestans</i> to its host
… inhibited in vitro and in planta by Brefeldin A (BFA), which is a conventional ER-to-Golgi-mediated secretion inhibitor. Wildtype cytoplasmic effectors follow an (BFA) insensitive secretion route for delivery into plant cells. <br/><br/>I hypothesised that extracellular vesicles (EVs) may be the …
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Capital structure and determinants of capital structure, before, during and after the 2008 financial crisis: A South African study
… in South Africa. Data extracted from INET BFA Expert database was analyzed using regression models on the correlation between the leverage and company size, growth, profitability, tangibility, liquidity, non-debt tax shield along with Ordinary Least Squares based on the sample of JSE listed …
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Predicting corporate turnaround of listed companies in South Africa
… 2007 to 2014 by using available data from iNet BFA. The financial distress model, Taffler's Z-score, is used to identify companies that fall within the sample. Multiple linear discriminant models with interaction variables are used as part of the process to derive the turnaround models. The …
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Debt leverage, company growth and job creation : South African manufacturing
… data primarily sourced from ÔMcGregor BFA Research DomainÕ. This analysis covered 74 publicly-listed South African companies which were from manufacturing, mining or construction sectors from 1992 to 2017. From this, it was found that debt leverage does not predict company growth or job …
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Migration of Nucleocapsids in Vesicular Stomatitis Virus-Infected Cells is Dependent on Microtubules and Actin Filaments
… glycoprotein of VSV in response to Brefeldin A (BFA) was used here to validate the BTBDM. This method was used to describe the distribution of the nucleocapsid of VSV during infection, and analyze the importance of the cytoskeleton on this distribution. To determine the mechanism by which …
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COORDINATION VARIABILITY AND INJURY RISK IN EXPERIENCED COLLEGIATE DANCERS
… were recruited from the dance major and minor, BFA major and minor, and recreational dancers who engaged in >3 hours of dance per week. At intake dancers completed 10 trials of a sauté jump task to measure baseline CV using a modified vector coding (MVC) approach. Dancers then completed 4 months …
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Identifizierung von Mikrodomän-Proteinen und funktionelle Charakterisierung von Cholesterin im Golgi-Apparat
… der Fusionsreaktion, wie die Verwendung von BFA im Intra-Golgi-Transportassay zeigt. Cholesterin findet sich sowohl in der liquid disordered als auch in der liquid ordered phase. Die Extraktion von Cholesterin erfolgt aus beiden Phasen in gleichem Maße. Im Unterschied dazu wird bei der Zugabe …
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The impact of administrative support, curriculum, student retention, population and production activity on theatre programs at historically black institutions: a case study perspective
… as conscientious and genuine. It offers the BFA degree in six areas of concentration. With 13 faculty and 188 students, the department offers an eclectic and diverse production season of plays. On the other hand Institution P will close its theatre program in the spring of 1997 because of low …
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Understanding adipokine secretion and adipocyte-macrophage cellular interactions, in search for the molecular basis of insulin sensitivity and resistance
… proteins and an intact Golgi apparatus, since BFA treatment inhibited secretion of both adiponectin and leptin. I found that trafficking of adiponectin is dependent on GGA1 coated vesicles. Endosomal inactivation significantly reduced adiponectin, but not leptin, secretion in both 3T3L1 and …
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Turnover Rate of The Neuronal Connexin Cx36 In Hela Cells
… of the pulse-labeled cells with Brefeldin A (BFA) prevented the addition of new connexins to junctional plaques, suggesting that the assembly of Cx36 into gap junctions involves the traditional ER-Golgi-TGN-plasma membrane pathway. In conclusion, Cx36-Halo is functional and has a turnover rate …
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The relationship between political risk, credit risk and profitability in the South African banking sector
… variables were obtained from the INET BFA dataset and the respective banks' official websites. Political risk data was provided by ICRG, while South African macroeconomic variables were obtained from the South African Reserve Bank (SARB) and Statistics South Africa (Stats SA). The …
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