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Showing 1 to 2 of 2 for “"BDNF Floxed Mice"”.
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SITUATION MOUSE ALL FLOXED UP: EXPLORING PHENOTYPIC ABNORMALITIES IN BDNF FLOXED MICE
… in the Ottem Laboratory became concerned when mice with LoxP sites flanking the BDNF gene depicted anxiety-like behaviors such as aggression, difficulty handling, and increased agitation. Though many studies have noted behavioral and phenotypic abnormalities related to large gene inserts, few …
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THE CHARACTERIZATION OF BEHAVIORAL ABNORMALITIES IN BDNF LOXP TRANSGENIC MICE
<p>BDNF homozygous floxed mice (BDNF<sup> lox+/+</sup>) are a transgenic mouse strain used to study the neurotrophin brain-derived neurotrophic factor (BDNF) through Cre-Lox recombination when crossed with the appropriate Cre-expressing strain. BDNF<sup> lox+/+</sup> mice contain two artificially …