Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"BCMA"”.
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Antioxidant system remodeling underlies off-target effects of anti BCMA-Targeted Immunotherapy in Multiple Myeloma [Il rimodellamento del sistema antiossidante è alla base degli effetti off-target dell’immunoterapia anti-BCMA nel Mieloma Multiplo]
… anticorpo-farmaco coniugato diretto contro BCMA, ha mostrato efficacia clinica nei pazienti recidivati o refrattari, ma è spesso limitato dallo sviluppo di resistenza e da effetti collaterali off-target. In questo lavoro di tesi è stato adottato un approccio integrato proteomico, …
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The Relationship Between Barcode Medication Administration Satisfaction and the Use of Workarounds Among Registered Nurses
… implemented barcode medication administration (BCMA) technology for RNs who have accepted this technology with varying levels of satisfaction. When nurses are dissatisfied with a BCMA system, they may find alternative methods to complete their work. Framed by the Technology Acceptance Model …
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Increasing Compliance of Bar Code Medication Administration in the Emergency Room
… room (ER). Bar-code medication administration (BCMA) has proven to be effective on the in-patient units in the hospitals researched and visited as part of this project, but the issue still remains that the emergency rooms exhibit a decreased compliance rate. The purpose of this Doctor of Nursing …
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Identifizierung, Charakterisierung und funktionelle Analyse der Bindungspartner von APRIL und TACI auf Monozyten und Dendritischen Zellen
… transmembrane activator and CAML interactor) und BCMA (engl.: B cell maturation antigen), die vor allem auf B-Zellen exprimiert werden und vor kurzem konnten Glykosaminoglykan (GAG)-Ketten von Proteoglykanen als dritter APRIL-spezifischer Bindungspartner auf Tumorzellen, B-Zellen und T-Zellen …
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Η προκλινική και κλινική ανάπτυξη του Belantamab Mafodotin για τη θεραπεία του Πολλαπλού Μυελώματος/The preclinical and clinical development of Belantamab Mafodotin for the treatment of Multiple Myeloma
… αντισώματος που στοχεύει το αντιγόνο BCMA (B-cell maturation antigen), το οποίο εκφράζεται επιλεκτικά στην επιφάνεια των κακοήθων πλασματοκυττάρων, προσφέροντας αυξημένη αντικαρκινική δράση με περιορισμένη επίδραση στους υγιείς ιστούς. Η ανάλυση των προκλινικών δεδομένων καταδεικνύει …
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Cell-Free Dna Sequencing In Multiple Myeloma
… plasma samples from 18 patients undergoing anti-BCMA chimeric antigen receptor T cell therapy (CAR-T). We observed similar concordance in the CAR-T cohort as in the newly diagnosed patients. In 14 evaluable patients, we observed no statistically significant decreases in variant allele fraction …
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Monogenetic Immune Dysregulation Syndromes and their Effect on the Plasma Cell Compartment
… Patients had decreased serum levels of BCMA, and a subset of patients had increased serum levels of BAFF. Both cytokines are involved in B cell maturation. II. As a model for the possible action of Abatacept, 8 treated patients with arthritis (RA) were studied. Abatacept is a biological …
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Uncovering hidden fronts of Africa’s liberation struggle: Black power, black consciousness, and South Africa’s armed struggle, 1967-1985
… of the Black Consciousness Movement of Azania (BCMA) and its armed wing the Azanian National Liberation Army (AZANLA) that emerged in the 1980s as the BC alternative to the non-racialist nominally socialist African National Congress of South Africa (ANC-SA) after previous movements failed to …
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Charakterisierung des Zytokins BAFF als wichtiger Regulator der B-Zellfunktion beim Haushuhn
… soluble form of the human BAFF-receptor BCMA (huBCMA-Fc) inhibited chBAFF binding. The addition of 293T cell derived chBAFF to splenic lymphocyte cultures led to a significant increase in B-cell viability. This dose-dependent effect was also observed in lymphocyte cultures from ceacal …