Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"BCL2 family proteins"”.
-
Androgen receptor-mediated growth suppression and apoptosis of human prostate epithelial cells
… analyses reveal that pro-apoptotic genes (BCL2L11/BIM, BOK and AIFM2) are androgen-induced, whereas pro-survival genes (BCL2L1/BCL-XL and MCL1) are androgen-repressed. Hence, we propose that the net effect of these AR-mediated expression changes shifts the balance of BCL2-family proteins in …
-
Single Cell Proteogenomics Analysis of AML Samples Treated with Decitabine and Venetoclax Reveals Divergent Treatment Escape Mechanisms
… we profiled the expression levels of various BCL2 family proteins through single-cell RNA sequencing. We studied four patients who had displayed the phenotypic shifts by DAb-seq analysis. At relapse, we confirmed the upregulated BCL2L1 in the predominant erythroid compartment in patient who …
-
Mechanisms of Erythroid Proliferation and Differentiation: Analysis of the Role of Erythropoietin Receptor in the Friend Virus Model
<p>Terminal erythroid differentiation is a precisely regulated process, in which mature red blood cells are generated from late erythroid progenitor cells. Regulation of cellular proliferation, survival and differentiation determines the fate of those cells. Extracellular signaling molecule, …