Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"BCL11B"”.
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Large Artery Stiffness: Genes and Pathways
… regulator B-cell CLL/lymphoma 11B (BCL11B) and non-coding RNA DB129663 representing potential targets for these enhancers. The association of five lead SNPs from the genome-wide association studies (GWAS) meta-analysis was examined for ex vivo aortic stiffness and BCL11B and DB129663 …
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Role of vascular smooth muscle Interleukin-11 in aortic aneurysm development
… Our laboratory examined wild-type (WT) and BCL11B knockout (BSMKO) mice treated with Angiotensin II (AngII) for a period of 7 days. The BSMKO mice given AngII exhibited aneurysm formation, while the WT mice did not show this response. RNA sequencing of entire aortas from BSMKO mice and WT …
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Role of Notch Signaling and GATA-3 in Establishing T-lineage Commitment and Survival in Developing Thymocytes
… specification for inducing expression of Bcl11b and directing early thymocyte proliferation and survival through repression of cell cycle-dependent kinase inhibitor 2b. Unlike Notch, GATA-3 was not required to inhibit B-lineage development but was crucial in preventing myeloid lineage …
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The use of lentivirus-mediated gene delivery to investigate the role of the Brain specific transcription factor MYT1L In-vitro and In-vivo
… with MYT1L during stem cell differentiation: BCL11B, MYT1, SYN1, SNAP25 and JPH3. Further in-silico analysis localized a MYT1L binding site in the promoter region of each one of those genes, suggesting that they might be direct targets of MYT1L. In order to expand our understanding of the …
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Role of ASCL1 and Its Interactors in Neuroblastoma
… differentiation during development, such as BCL11B, PBX1, PHOX2B, SOX11, and others. On the other hand, in the cell lines less responsive to ASCL1-induced differentiation, ASCL1 associated more with proteins involved in cell-cycle regulation, such as CDKs and cyclins, or showed weaker …