Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"BCL-6"”.
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Expression of Follicular Helper T-cell Markers in Primary Cutaneous T-cell Lymphoma
… (ICOS); and the transcription factor Bcl-6. The TFH-cells appeared to be localized in several subsets of T-cell lymphomas. However, their localization in cutaneous T-cell lymphomas has been rarely described. In this study, the clinical features, histopathological morphology, and …
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Insights Into the Regulatory Requirements for T Follicular Helper Cell Development
… of the TFH lineage defining transcription factor Bcl-6. Intriguingly, our work established that signals from IL-12 were required for both the differentiation and function of this TFH-like population. Mechanistically, IL-12 signals are propagated through both STAT3 and STAT4, leading to the …
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Transkriptionelle Regulation des CD23a-Promotors in Zellen chronischer lymphatischer Leukämien vom B-Zelltyp
… Signaltransduktionswege; auch Proto-Onkogene wie bcl-6 und Notch2 sind bei der Expression von CD23 von Bedeutung. Deren Rolle für die Pathogenese der B-CLL muss noch untersucht werden.
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Analyse genomischer Aberrationen gastraler Marginalzonen B-Zell-Lymphome vom MALT-Typ
… gastraler Marginalzonen B-Zell Lymphome (MZBCL) vom MALT-Typ ist derzeit noch unklar. Ein unbekannter Teil dieser niedrig-malignen Lymphome transformiert zu hoch-malignen gastralen „diffusen großzelligen B-Zell Lymphomen“ (DLBCL), jedoch besitzen diese DLBCL nicht die Translokation …
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The Role of IkZF Factors in Mediating TH1/TFH Development and Flexibility
… Aiolos in turn collaborate with STAT3, induces Bcl-6 expression within these cells, thus promoting these cells to exhibit characteristic features of TFH cells. The work in this dissertation hopes to advance our understanding of the regulatory mechanisms involved in cytokine mediated T-cell …