Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"BCAP"”.
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Regulation of inflammatory TLR signalling by the BCAP adaptor
BCAP is a PI3K adaptor protein in TLR, BCR and IL-1R and TCR signalling. In TLR signalling, BCAP acts as a negative regulator of inflammatory signalling. Regulation of TLR signalling is essential as overstimulation can cause excessive and pathological inflammation, which leads to serious illnesses …
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The role of BCAP in regulating the TLR signalling pathway
… TIR-domain-containing adaptors MAL and MYD88. BCAP (B-cell adapter for PI3K) was identified as a negative regulator in the TLR4 MYD88-dependent signalling pathway. This study utilises biochemical, biophysical and structural biological techniques and focuses on two hypotheses to elucidate the …
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Regulation of Reparative Macrophage Transition by the B-cell Adapter for PI3K (BCAP)
… is dictated by B-cell adapter for PI3K (BCAP). Mice harboring a macrophage specific deletion of BCAP fail to recover from and succumb to DSS-induced colitis due to prolonged intestinal inflammation and impaired tissue repair. Following microbial stimulation, gene expression in WT …
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T Cell Intrinsic BCAP Links IL1R to the PI3K-mTOR Pathway and Regulates Pathogenic Th17 Differentiation
… B cell adaptor for phosphoinositide 3-kinase (BCAP) and determined a role for BCAP in the TLR signaling pathway in myeloid cells. Due to the shared use of TIR domains by TLR and IL1R signaling pathways, I hypothesized that BCAP would also be involved in signaling downstream of the IL1 family of …
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B-Cell Adapter for Phosphoinositide 3-Kinase Is a Signaling Adapter in the Toll-Like Receptor/Interleukin-1 Receptor Superfamily
… a novel TLR/IL1R signaling adapter, termed BCAP (B-cell adapter for PI3K), which was identified based on the presence of a cryptic N-terminal TIR domain. I show here that BCAP (B-cell adapter for PI3K) contains a functional TIR domain enabling its participation in the TLR signaling pathway. …
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Culvert Hydraulics: Comparison of Current Computer Models
… X-ing, Broken-back Culvert Analysis Program (BCAP), Hydraflow Express, Culvert Master, Culvert, and Hydrologic Engineering Center River Analysis System (HEC-RAS). While all of these programs can simulate the behavior of flow through a culvert, slightly different methodologies are utilized …
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An assessment of the impact of landscape soil, government programs and crop insurance on the profitability of perennial grass cropping systems grown for bioenergy
… programs like Biomass Crop Assistance Program (BCAP), and crop insurance affect the decision to plant bioenergy crops. The analysis assumes that the producers are risk averse and seek to maximize utility. Results show that perennial grasses grown for bioenergy have a higher relative …
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Modifying a Cow-Calf Biophysical Simulation Model for Analyses of Alternative Enterprises
… policies, the Biomass Crop Assistance Program (BCAP) and a Carbon Offset Program (CO), encourage the production of switchgrass and policy outcomes are most favorable when land of adequate quality is chosen to support higher switchgrass yield. At lower yield levels, the inclusion of switchgrass …
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Biomass energy crop production and residential pellet consumption in the midwestern U.S.
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