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Showing 1 to 3 of 3 for “"BBD18"”.
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A Molecular Genetic Investigation of the Regulation of Outer Surface Protein C in Borrelia Burgdorferi: Identification and Characterization of the Novel Regulatory Protein BBD18
… molecular genetic approaches, we identified BBD18 as a novel factor that has the potential to negatively regulate OspC. Expression of BBD18 in B. burgdorferi repressed transcription of ospC and abrogated infection in mice. We determined that BBD18 likely interfaces with the central …
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A Molecular Genetic Investigation of the Regulation of Outer Surface Protein C in Borrelia Burgdorferi: Identification and Characterization of the Novel Regulatory Protein BBD18
… molecular genetic approaches, we identified BBD18 as a novel factor that has the potential to negatively regulate OspC. Expression of BBD18 in B. burgdorferi repressed transcription of ospC and abrogated infection in mice. We determined that BBD18 likely interfaces with the central …
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Coping with stress: How Reactive Oxygen and Nitrogen Species alter the transcriptional landscape of the Lyme disease spirochete Borrelia burgdorferi
… Additionally, we observed elevated expression of bbd18 by RT-qPCR and increased concentrations of BBD18 protein through western blot analysis in B. burgdorferi exposed to H2O2 and sper/NO with and without a pH shift, but NO more strongly induced BBD18 as compared to H2O2 regardless of pH shift or …