Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"BAR proteins"”.
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Cip4 and Src In Promoting The Migration and Invasion of Breast Cancers
… early step in the metastatic cascade, and many proteins have been identified as part of an “invasive signature.” The non-receptor tyrosine kinase Src is commonly upregulated in breast cancers, often in conjunction with overexpression of EGFR. Signaling from this pathway stimulates cell …
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Mechanics, shape, and programmability in soft matter systems: From fluid membranes to spring and droplet networks
… in yeast involves clathrin, actin, and Bar proteins. Our model breaks up the process into three stages: (i) initiation, where clathrin interacts with the cell membrane via adaptor proteins, (ii) elongation, where the membrane is then further deformed by polymerizing actin filaments, …
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Computational investigations of protein dynamics and its implication in cellular functions: two cases on membrane sculpting by protein complexes and molecular origin of Parkinson's disease
Proteins are complex machineries dedicated to drive many functions in eukaryotic cells. In this article, two cases of protein dynamics and their implications to cellular functions are discussed with computational approaches: membrane sculpting by F-BAR domains and transient β-hairpin structure in …
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Toca-1 driven actin polymerisation at membranes
… for the formation of these protrusions. The proteins that are thought to fulfil such a role have a membrane interacting domain (such as the PH domain in lamellipodin, or I-BAR protein in IRSp53) and a domain which interacts with actin regulatory proteins (such as the SH3 domain of IRSp53, …