Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 173 for “"BALB/c mice"”.
-
The Effects of Electrochemical Therapy on Colon-25 Tumors in Balb-C Mice
… of the research was to treat immunodeficient mice, implanted with colon-25 tumors, with continuous and interrupted electrochemical therapy (ECT). ECT involves the placement of two electrodes, an anode near the center of the tumor and a cathode into the tumor periphery. A constant voltage is …
-
Investigation of Bone Marrow Hematopoietic Stem Cell Migration during Inflammation in BALB/c Mice /
… stem cells and their migration in the BALB/c mouse contact hypersensitivity model in vivo. It was found that isolated hematopoietic cell populations had a significant anti-inflammatory effect and inhibited the edema. The studies showed that the most efficient (up to 66%) inhibition of …
-
Dietary Omega-3 Fatty Acids, Cell-Mediated Cytotoxicity and Anti-Tumorigenic Activity in Balb/c Mice
… greater in LO-fed compared to control mice fed corn oil (CO).
-
Effects of Daily Oral Injections of Quercetin on Implanted Colon-25 Tumor Growth in Balb-C Mice
… mg) of quercetin on Colon-25 tumors implanted in Balb-c mice were studied. The data in this study show that: (1) certain dosages of quercetin in alcohol solutions, reduces the weight, and size of implanted Colon-25 tumors in Balb-c mice, (2) these same dosages of quercetin all produce a profound …
-
Deletion of IL-4 receptor alpha on dendritic cells renders BALB/c mice hypersusceptible to Leishmania major infection
In BALB/c mice, susceptibility to infection with the intracellular parasite Leishmania major is driven largely by the development of T helper 2 (Th2) responses and the production of interleukin (IL)-4 and IL-13, which share a common receptor subunit, the IL-4 receptor alpha chain (IL-4α ). While …
-
Immunochemical and Idiotypic Analyses of Immunological Components of an Immune Network in BALB/c Mice and Its Application to Anti-Dna Autoimmunity
The sequential occurrence of self-directed antibodies is predicted by the immune network theory of Jerne (1974). According to this theory, antibodies that are specific for the variable regions of inducing antibodies are maintained in equilibrium until the balance within the immune network is …
-
Assessment of the Expression of Brucella Abortus Heat Shock Protein, Groel, in Vaccinia Virus to Induce Protection Against a Brucella Challenge in Balb/C Mice
… confirmed by immunoblotting. Groups of 5 female BALB/C mice were injected with the vaccinia recombinant or appropriate positive and negative control vaccines. Mice were bled and their humoral immune responses assessed. In addition, mice were challenged with virulent B. abortus strain 2308 and …
-
The Effect of Dietary Fat Level on Tumor Development and Immunity in BALB/C Mice Fed Casein of Wheat Gluten as Protein and Challenged with Herpes Type 2-transformed Cells
… In previous work done in this laboratory with BALB/c mice injected with herpes simplex Type 2-transformed mouse cells (H238), the effects of a diet which greatly enhanced tumor growth was compared with one which restricted tumor growth. The latter, a low (5%) fat, low protein diet, in which the …
-
The identification and characterization of two murine genes regulated by the level of dietary fat
… library constructed from mammary gland tissue of BALB/c mice fed a low fat diet (Elliott et al. 1993. Biochim. Biophys. Res. Comm. 190: 167-174). Northern hybridization analyses of hepatic total RNA from BALB/c mice fed diets containing 0, 5, 10, 15 or 20% corn oil showed a significant …
-
Investigating the role of IL-4/IL-13 signalling through the IL-4 receptor alpha (IL-4Rα) on keratinocytes in murine models of Leishmania major and Schistosoma mansoni
… IL-4 secreted early during L. major infection in mice, can drive a Th1 response by instructing dendritic cells to produce IL-12. Additionally, keratinocytes at the site of L. major infection in C57BL/6 mice, were postulated to be the source of the IL-4. We investigated if IL-4/IL-13 signalling via …
-
The influence of maternal Nippostrongylus brasiliensis infection on immunity in offspring
… offspring. We show that maternal Nb infection in BALB/c mice results in the transfer of Nb antigen (NES)-specific IgG1 in utero and through breastmilk, changes in lymphocyte populations and early germinal center formation in naive offspring. Maternal Nb infection does not interfere with control of …
-
A study of immune responses to Leishmania mexicana antigens and immunogenicity of L. donovani Centrin-3
… (SLA1&2) was investigated by immunisation of Balb/c mice and challenge with live L. mexicana and an in vitro immunological analysis. Immunisation of Balb/c mice with SLA mixed with IFA adjuvant significantly protected against challenge with live L. mexicana parasites.
-
Macrophage Suppression Across Genetic Barriers By a Spleen Cell Culture Derived Factor
… by spleen cells obtained from C57BL/10J and BALB/c mice and an assay for the maintenance of biological activity across genetic barriers. Suppression of phagocytic activity of C57BL/10J PEC by MSF derived from BALB/c mice and likewise, activity of BALB/c PEC with MSF from C57BL/10J mice was …
-
The role of CD4+T cells in host protective responses against cutaneous Leishmaniasis using genome-wide transcriptomics.
… or presence of IL-4Rα signaling. Non-healer BALB/c mice with a deletion of the IL-4Rα on all cells (IL-4Rα-/-) or CD4+ T cells only (iLCKcreIL-4Rαlox/-) and their controls (wild-type (WT) C57BL/6, WT BALB/c and littermate IL-4Rαlox/-) were subcutaneously infected with L. major. As expected, …
-
Mechanisms of IFN-gamma-mediated Resistance against Development of Toxoplasmic Encephalitis
… models of reactivation of chronic infection in BALB/c mice. This strain of mouse is genetically resistant to T. gondii infection and establishes a latent chronic infection as do immunocompetent humans, and therefore provides an excellet model for this purpose. Our laboratory previously …
-
The role of Cysteinyl leukotriene type 1 receptor (CysLTR1) during Listeria monocytogenes and mycobacterium tuberculosis infections in mice
… CysLTR1 in disease progression using C57BL/6 and Balb/c mice infected either with Listeria monocytogenes (Lm) or with Mycobacterium tuberculosis (Mtb). Using CysLTR1 knockout (Cysltr1-/-) mice, we conducted time course and survival studies on both C57BL/6 and Balb/C genetic backgrounds. Our …
-
Melioidis: an investigation of cellular immune responses
… Following intravenous (iv) inoculation, BALB/c mice are highly susceptible, and C57BL/6 mice relatively resistant to B. pseudomallei infection. Using the murine model, we compared the pathogenesis of B. pseudomallei infection following inoculation of the bacterium by iv, intraperitoneal …
-
Nterleukin-4 responsive dendritic, macrophage/neutrophil cells are dispensable for host resistance against Leishmania Mexicana infection in mice
… This has been demonstrated in studies involving BALB/c mice deficient in IL-4, IL-13, and IL-4Rα infected with L. mexicana. To determine the specific cell in IL-4Rα-/- BALB/c mice that contribute to the control of L. mexicana infections, studies on cell-specific IL-4Rα deficient mice need to be …
Page 1 of 9