Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"BAEC"”.
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In Vitro Binding and Transport Regulation by Endothelial Cells: Preliminary Studies looking at FIX and IGF-I
… receptors) to bovine aortic endothelial cells (BAECs). Competitive binding experiments between 125I-FIX and FIX were undertaken to quantify the interaction of recombinant and transgenic FIX with BAECs and human collagen IV and determine if there was a measurable difference in binding affinity. …
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Development and Characterization of an In-House Custom Bioreactor for the Cultivation of a Tissue Engineered Blood-Brain Barrier
… bioreactor, to ultimately allow co-cultures of BAEC and C6 glioma cells, and further the progression toward creating an in vitro model of the BBB.</p> <p>The work of this thesis demonstrates development of an in-house custom bioreactor system that can successfully culture cells. Results showed …
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Kinetics study of heat shock protein 70 expression
… kinetics. Bovine aortic endothelial cells (BAEC) were heated in a 42oC incubator for up to 5 hours and subsequently held at 37oC for up to 48 hours. Western blot and quantitative protein analysis were performed to measure the extent of HSP70 expression kinetics as a function of heating …
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An Intramural, Tension-modulating Reflex in the Rat Caudal Artery
… isolated, bovine aortic endothelial cells (BAEC) exposed to EES relaxed denuded RTA and could be blocked by L-NAME, MB, KCl, and TEA. L-arginine reversed the effect of L-NAME as in the ring experiments. EFS-induced relaxation of intact, pressurized, and PE preconstricted RTA was frequency …
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Differentielle Genexpressionsanalyse aktivierter Endothelzellen
… in vitro-Modell boviner Aortenendothelzellen (BAEC) zum Einsatz, bei dem zwei aktivierte, subkonfluent proliferierende Zellpopulationen ohne und mit Zytokinstimulation (bFGF, Fibroblasten-Wachstumsfaktor II) gegenüber zwei konfluent arretierten Populationen ohne und mit Inhibitor …
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The role of death-associated protein kinase in endothelial apoptosis under fluid shear stress
… the impact of lamin deficiency in both MEF and BAEC cells on DAPK activity and apoptosis. We investigated the normally positive effects of shear on lamin deficient cells. The loss of lamin expression made cells more susceptible to shear stress and increased overall cell turnover compared to …
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Case roles / relations and discourse relations: A Maori language-based perspective
The overall aim of this research project is to explore case roles/ relations and discourse relations (referred to in this thesis as 'intra-propositional relations' and 'interpropositional relations' respectively) from the perspective of the Maori language. The thesis begins with an outline of the …
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Mechanisms of hot gas ingestion in turbine disk cavities
In a gas turbine engine, hot gas ingestion occurs when gas from the mainstream flow path migrates into the cavities between stator and rotor disks. In order to mitigate the damage caused by these high-temperature gases, the cavities are purged with colder air from the compressor, and rim seals are …
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Towards understanding the mechanisms behind mRNA localisation in growing axons
During embryonic nervous system assembly, mRNA localisation is precisely regulated in growing axons, affording subcellular autonomy by allowing controlled protein expression in space and time. Different sets of mRNAs exhibit different localisation patterns across the axon. Little is known, however, …
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Antecedents and consequences of motivation: an examination of motivation as mediator to human and organisational performance
Organisational behaviour researchers studied the link between motivation factors as input variables (e. g. work environment) and employee behaviour measures as output variables (e. g. individual performance) without taking into consideration the construct of human motivation as a mediator. …
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Composite low temperate hydrogen storage material on the basis of iron-titanium alloy ; synthesis and structure
It is widely believed that hydrogen will within a few tens of years become the means of storing and transporting energy. The reason is the depletion of hydrocarbons and the relatively facile production of hydrogen from various renewable sources of energy. Hydrogen can be combusted in an efficient …
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Modeling Astrophysical and Large-Scale Structure Signatures in Axion Cosmologies
The quest to understand the fundamental nature of dark matter (DM) remains a challenge in contemporary physics. This thesis aims at elucidating astrophysical and cosmological imprints of fuzzy dark matter (FDM), a promising class of models which find ample motivation within theories of particle …