Global ETD Search
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Showing 1 to 3 of 3 for “"BACtrap"”.
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The Diversity of Cortical Interneurons
… hard to classify them without markers. We took a BACtrap approach performing translating ribosome affinity purifications on transgenic mice with Bacterial artificial chromosome, for systematic discovery of markers for different cell types. First, we generated BACtrap lines for known markers of …
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Cell-Type Specific Translational Profiling in Huntington's Disease Mouse Models
… pre- and post-symptomatic time points using the BACTRAP technique (Heiman et al, 2008). We re-characterized the behavioral phenotype of the HD model mice on the D1 and D2 TRAP backgrounds and found many changes in the translated mRNA profiles of these two classes of medium spiny neurons, …
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Molecular and Functional Characterization of Pyramidal Cell Types in the Frontal Cortex of Mouse Brain
… protein L10 and Cre recombinase. We generated bacTRAP transgenic mice for six pyramidal cell types in the neocortex distinct by marker expression, areal/laminar topography, connectivity and cell morphology. These include corticocortical neurons in upper layer 2 of neocortex defined by genes …