Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"BACE Inhibitor"”.
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The Processing of Amyloid Precursor Protein in the Central Nervous System of Humans and Rhesus Macaques
… intervention of the β-secretase pathway by a BACE1 inhibitor would affect the α-secretase pathway. Soluble APPβ, sAPPα and Aβ were isolated from rhesus macaque CSF by serial immunoprecipitation. Monkeys were undergoing stable isotope labeling kinetics studies. Isolated APP metabolites …