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Showing 1 to 3 of 3 for “"B7-H3"”.

  1. Development and Characterization of B7-H3-Targeted Radioimmunotherapies For The Treatment of Solid Tumors

    … Herein, we characterize novel<sup> </sup>anti-B7-H3 immuno-conjugates for PET imaging and RIT of solid tumors in preclinical models.</p> <p>Human B7-H3 (CD276) protein is highly expressed on solid tumor cell surfaces and endovascular surfaces in a wide variety of cancers (colon, breast, …

    uthsc Repository record for Development and Characterization of B7-H3-Targeted Radioimmunotherapies For The Treatment of Solid Tumors (opens in a new tab)

  2. Helicobacter pylori Type 4 Secretion System Modulates Host T Cell Responses

    … our lab showed that H. pylori up-regulates B7-H1 (a T cell co-inhibitory molecule) expression on GEC, which, in turn, suppress T cell proliferation and effector function, and induce Treg cells in vitro. My studies showed that, along with B7-H1, GEC expresses B7-H2 and B7-H3 molecules. B7-H2 …

    utmb Repository record for Helicobacter pylori Type 4 Secretion System Modulates Host T Cell Responses (opens in a new tab)