Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"B7-H3"”.
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Development and Characterization of B7-H3-Targeted Radioimmunotherapies For The Treatment of Solid Tumors
… Herein, we characterize novel<sup> </sup>anti-B7-H3 immuno-conjugates for PET imaging and RIT of solid tumors in preclinical models.</p> <p>Human B7-H3 (CD276) protein is highly expressed on solid tumor cell surfaces and endovascular surfaces in a wide variety of cancers (colon, breast, …
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Helicobacter pylori Type 4 Secretion System Modulates Host T Cell Responses
… our lab showed that H. pylori up-regulates B7-H1 (a T cell co-inhibitory molecule) expression on GEC, which, in turn, suppress T cell proliferation and effector function, and induce Treg cells in vitro. My studies showed that, along with B7-H1, GEC expresses B7-H2 and B7-H3 molecules. B7-H2 …
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Immune checkpoints in oral carcinogenesis
… in OSCC. Seven of them (ALHD1, FKBP51, PD-L1, B7-H3, B7-H4, B7-H6, and IDO1) had been reported as adverse prognostic factors and five (CTLA-4, PD-1, PD-L2, TLT-2 and VISTA) did not have prognostic value. Only two molecules, PD-L1 and B7-H3, had sufficient data for conducting a meta-analysis. …