Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"B56"”.
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PP2A-B56 isoform specificity at the centromere and kinetochore
… mitotic processes are regulated by the PP2A-B56 phosphatase complex: the Spindle Assembly Checkpoint (SAC), kinetochore-microtubule attachments and sister chromatid cohesion. We show here that these key functions of PP2A-B56, which require its localization to either the kinetochore or …
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The functional and molecular characterisation of the novel DNA damage repair protein Bod1L
… central role in DDR by controlling MDC1 and PP2A-B56 localisation to damaged DNA. Bod1L depletion leads to micronuclei formation in undamaged cells and hypersensitivity to genotoxic stress. Bod1L binds to chromatin and is phosphorylated by ATM at sites of DNA damage. In Bod1L-depleted cells, ATM …
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Kansas blister beetles (Coleoptera: Meloidae): historical and alfalfa field survey results
Call number: LD2668 .T4 ENTM 1987 B56
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Kansas blister beetles (Coleoptera: Meloidae): historical and alfalfa field survey results
Call number: LD2668 .T4 ENTM 1987 B56
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Role of phosphatases in the end-on conversion process
… phosphatases - BubR1- recruited PP2A-B56 and KNL1-recruited PP1 - in counteracting Aurora B kinase during the end-on conversion process. I found that BubR1-recruited PP2A-B56 plays an essential role in the process, but KNL1-recruited PP1 does not. I also investigated whether the …
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Regulation of Substrate Degradation and Cancer Metabolism by the Fbw7 Ubiquitin Ligase
… its own degradation. We found that the PP2A-B56 phosphatase specifically opposes autophosphorylation of cyclin E at S384, and this dephosphorylation stabilizes catalytically active cyclin E-CDK2 complexes at the G1/S transition. siRNA-mediated depletion of PP2A-B56 is sufficient to decrease …
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The Role of Protein Phosphatases in Regulation of Drosophila S6 Kinase by Nutrient Signaling Pathways
… ablation of two other gene products, the PP2A-B56-2 regulatory subunit and the dPP4 catalytic subunits, results in hypophosphorylation of dS6K during amino acid starvation, suggesting that the activities of these two gene products are required for maintenance of nutrient signaling pathways and …
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Eukaryotic chromosome segregation: New aspects of separase regulation by securin, Cdk1, PP2A and auto-cleavage
… and bridged by separase, and that it is the B56- and not the B55-isoform of PP2A which associates with the separase-securin complex. Moreover, free securin is shown to be degraded in early mitosis in a phosphorylation- and APC/C-dependent manner, while separase-associated securin is kept …
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A formal and stylistic analysis of selected compositions for solo accordion, with accompanying ensembles by twentieth-century American composers, with implications of their impact upon the place of accordion in the world of serious music
The accordion, a little known instrument in the world of serious or art music, does possess enormous capacities for artistic expression of the highest order.In the twentieth-century, some accordionists began to realize the instrument's potential. These accordionists made transcriptions of the …