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Showing 1 to 5 of 5 for “"B200 - Pharmacology, toxicology & pharmacy"”.

  1. Discovery of acoustic emission based biomarker for quantitative assessment of knee joint ageing and degeneration

    Based on the study of 34 healthy and 19 osteoarthritic knees in three different age groups (early, middle and late adulthood), this thesis reports the discovery of the potential of knee acoustic emission (AE) as a biomarker for quantitative assessment of joint ageing and degeneration. Signal …

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  2. Full of empty promises? Exploring what drug use achieves for the individual

    This qualitative study begins with the research question - What does drug use achieve for the individual? For many years now, research into drug using behaviour has tended to focus on developing theories to explain why individuals use drugs, yet directly asking an individual why they participate in …

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  3. Pharmacokinetics and pharmacodynamics of some NSAIDs in horses: A pharmacological, biochemical and forensic study

    Non-steroidal anti- inflammatory drugs (NSAIDs) have been in use for over 100 years to treat pain, exerting their analgesic effect by inhibiting prostaglandin (PG) synthesis via the COX pathway. Some of the NSAIDs have adverse side effects including ulceration of the stomach and cardiovascular …

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  4. Hair analysis for drugs of abuse

    … abuse is the first step in clinical and forensic toxicology. There are a large number of controlled substances and doping agents and novel compounds, which have yet to be characterised. A series of screening methods for drugs of abuse in hair were developed using LC-MS/MS and GC-MS/MS. Using our …

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  5. The Power Output Characteristics of Downhill Mountain Biking

    Purpose: To determine the performance characteristics of field-based Downhill Mountain biking (DH) and to identify the best methods of assessment for DH type activity. Methods: Twelve trained male cyclists of differing experience levels (age 31.4 ± 9.8 yrs, mean ± s.d.), performed a single …

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