Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"B110 - Anatomy"”.
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Biochemical differences in the modes of synaptic vesicle release between control and streptozotocin-induced diabetic rats and possible relationship to changes in behaviour
In order to understand the huge complexity of brain function, and to determine the mechanisms underlying various psychiatric (e.g. schizophrenia) and neuronal disorders (Alzheimer’s disease), it is imperative that the basic machinery involved in neuronal transmission is fully elucidated. This …
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The Impact of Post-Intimate Stalking on the General Sexual and Relational Life of Victims.
The Impact of Post-Intimate Stalking on the General Sexual and Relational Life of Victims. Background: Research to date indicates that intimate stalking is a significant public health problem. Studies illustrate the psychological, occupational and mental health impact on a victim’s health. There …
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Telomerase a prognostic marker an therapeutic target
Malignant glioma is the most common and aggressive form of tumours and is usually refractory to therapy. Telomerase and its altered activity, distinguishing cancer cells, is an attractive molecular target in glioma therapeutics. The aim of this thesis was to silence telomerase at the genetic level …
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Investigation into the potential of methylene blue and its derivatives to be used in the photodynamic therapy of non-pigmented and pigmented cells
Photodynamic therapy (PDT) is a novel treatment for malignant disease. The first step is intravenous injection of a light-absorbing, cytotoxic drug (the photosensitizer) that is then allowed time to accumulate in malignant tissue. The second step involves local activation of the photosensitizer …
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Drug delivery systems to include liposomes and microparticles in order to aid treatment of glioma.
Targeted drug delivery is achieved by enhancing drug availability at the response site while minimising its availability at other sites, especially those that manifest toxicity. The effects of liposomes and polymeric nanoparticles in cancer chemotherapy have been investigated in recent years and …
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Role of Cell Death Regulatory Genes and Radiation Response in Pancreatic Adenocarcinomas
Gene expression studies have revealed that there is more than one cellular pathway governing growth inhibition and apoptosis. Mutations in the ras oncogene that(activate ras) are known to lead to the inactivation of genes that are directly involved in these pathways of growth inhibition and …