Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"B-type natriuretic peptide"”.
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Impaired tissue responsiveness to B-type natriuretic peptide in heart failure: biochemical bases.
Release of the B-type natriuretic peptide (BNP) is increased in heart failure (HF). Physiologically, BNP exerts natriuretic, diuretic, vasodilator and cardioprotective effects. A number of clinical investigations carried out with synthetic BNP for the treatment of HF have suggested that BNP-based …
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Peri-operative cardiac morbidity: prediction, prevention and the novel role of B-type natriuretic peptide
… in the literature regarding the role of B-type natriuretic peptide (BNP) in the prediction of cardiac events in non-cardiac surgical patients; despite the fact that its measurement has been shown to be an important prognostic tool in both non-surgical and cardiac surgical cohorts. In this …
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Clinical utility of B-type natriuretic peptide (NP) in paediatric cardiac surgery: a systematic review
B-type natruiretic peptide (NP) is a biomarker that has gained widespread use in several patient populations and clinical situations. It is a hormone secreted primarily by ventricular myocytes in response in myocyte stretch or ischaemia.
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Using B-type natriuretic peptide and whole body contrast enhanced magnetic resonance imaging to detect asymptomatic cardiovascular disease and improve prediction of risk of cardiovascular disease: the TASCFORCE Study
… pre-clinical cardiovascular disease using B-type natriuretic peptide (BNP) and whole body contrast enhanced magnetic resonance imaging (MRI) could identify those at low/intermediate risk or disease who will develop clinical disease and thus facilitate improved targeting of primary prevention …
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Building improved risk stratification models for patients post non ST-segment elevation acute coronary syndrome using ambulatory ECG data
… in clinical settings, such as TIMI risk score, B-type natriuretic peptide, and left ventricular ejection fraction (adjusted hazard ratio for one-year death (95% Cl): 5.25 (1.42, 21.2)). This model is unique in its simplicity, as it relies on simple logistic regression with only three features, …
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ZFP36L3: a Unique Member of the Tristetraprolin Family of RNA-Binding Tandem Zinc Finger Proteins
… relative enrichment and sequence analysis, was B-type natriuretic peptide, a hormone well-known for its role in cardiac physiology. We confirmed the expression of B-type natriuretic peptide in mouse placenta through northern blotting and in situ hybridization histochemistry. We also verified the …
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Responding to resynchronization : improving the impact of biventricular pacing in the management of chronic heart failure
… protein are reduced after CRT. N-terminal Pro B-type natriuretic peptide appears limited as a marker of CRT response. Chapter 5 investigates the haemodynamic value of temporary biventricular pacing after coronary artery bypass grafting and concludes that it cannot be recommended routinely even in …
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Biomarkers of Cardiovascular Disease in Renal Transplant Recipients
… (CRP), troponin T (TnT), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and soluble ST2 (sST2) were measured from stored plasma/serum samples and investigated for an association with these outcomes. Discrimination metrics were derived to quantify the incremental value of adding …
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Regulation of natriuretic peptide system activation:effects of spontaneous natriuretic peptide mutations and identification of novel natriuretic peptide receptor phosphorylation sites.
… that mediate the physiologic effects of natriuretic peptides, including reduction of blood pressure and blood volume, stimulation of long bone growth, and regulation of cardiac size. Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) signal through GC-A while C-type …
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Acute heart failure: Scottish temporal trends in hospitalisation, outcomes and clinical application of natriuretic peptides
… failure is essential to improving outcomes and natriuretic peptides (NPs) are the recommended biomarkers for diagnosis of AHF. NP concentrations are known to be altered by patient factors, such as age, renal impairment and arrhythmia, which are common in populations with heart failure. The …
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The Effect of Allopurinol on Left Ventricular Mass in Patients with Treated Essential Hypertension
… substances (TBARs), N-terminal prohormone B-Type Natriuretic Peptide (NTproBNP), Procollagen type I carboxy-terminal Propeptide (PICP) and soluble ST2 (sST2) and other CMRI parameters. <br/><br/>The two groups were well matched at baseline, importantly there were no statistically significant …
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Neurohormonal and inflammatory markers in valvular heart disease
… Numerous studies demonstrate that increased natriuretic peptide plasma levels, including atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP) and amino-terminal BNP (N-BNP) reflect left ventricular dysfunction, correlate with symptoms of cardiac failure and are independent …
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Implementation of global miRNA biomarker discovery in human plasma
… the discriminatory power of current AF markers B-type natriuretic peptide (BNP) and collagen 3 synthesis marker PIIINP. miRs 144-3p, 142-5p and 660-5p were shown to be significantly downregulated in individuals with AMD compared to healthy controls. Hierarchical clustering analysis of isomiR data …
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Age and gender differences in risk factor burden, myocardial dysfunction and cardiovascular events in relation to glucose metabolism
… possible associations between N-terminal pro-B-type natriuretic peptide (Nt-proBNP) and FG as a continuous variable and in FG groups (as in Paper I) were assessed in the MPP-RES echocardiography subcohort. A positive correlation was found between Nt-proBNP and FG among middle-aged men. A …