Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"B-cell Non-Hodgkin-Lymphoma"”.
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Investigating heterogeneity and mechanisms of resistance in paediatric B-cell non-Hodgkin lymphoma
Paediatric mature B-cell non-Hodgkin lymphoma (B-NHL) is a highly aggressive disease with one of the fastest growth rates of any human malignancy. The subtypes are Burkitt and Burkitt-like lymphoma/leukaemia, diffuse large B-cell lymphoma and primary mediastinal B-cell lymphoma; with Burkitt …
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Clinical-pathological characterisation of children with B-cell non-Hodgkin lymphoma over a ten year period at a tertiary centre in Cape Town
Background: We characterized B-cell non-Hodgkin lymphoma (NHL) cases over ten years at a tertiary children's hospital to contribute to the body of knowledge on pediatric lymphoma in developing countries with a high human immunodeficiency virus (HIV) burden. Methods: A retrospective cohort study …
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Efficacy of Dual Cd19-Cd79B Car In B-Cell Malignancies
… responses, about 30%-60% of patients with B-cell malignancies relapse following CD19-targeting chimeric antigen receptor (CAR) T cell therapy. CD19 loss is a major cause of relapse and resistance after CD19 CAR T therapy. Dual antigen targeting could overcome resistance due to antigen escape …
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Understanding the molecular pathogenesis of HIV-associated Burkitt Lymphoma – the impact of HIV-1 protein Tat on lymphoma driver genes
Burkitt Lymphoma (BL) is a B cell non-Hodgkin lymphoma that occurs as three distinct subtypes, namely: endemic, sporadic, and immunodeficiency/HIV-associated. This cancer represents a frequent cause of mortality among HIV+ people in Southern Africa which has the highest incidence of HIV/AIDS …
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Evaluierung des Antibody Directed Enzyme Prodrug Therapy-Konzepts im Mammakarzinom- und Lymphom-Mausmodell
… syngenes Lymphom-Modell mit hochmalignem B-Zell Non-Hodgkin-Lymphom in Balb/c-Mäusen unter Verwendung von murinen A20-Zellen untersucht. Es wurden die Antikörper anti-uPAR und anti-CD19 für den Transport von β-D-Galaktosidase an den Tumor verwendet. Um die ADEPT zu evaluieren wurden die …