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Showing 1 to 1 of 1 for “"B-Lymphocyte Subsets"”.
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The Role of Foxo Transcription Factors in B Cell Development and Activation
… controlled via Akt. When a mature B lymphocyte is stimulated through the BCR, Akt-mediated phosphorylation of Foxos results in their exclusion from the nucleus. In the absence of Foxo nuclear activity, the B cell progresses into the cell cycle. We have discovered a second …