Global ETD Search
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Showing 1 to 2 of 2 for “"B cell metabolism"”.
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DEPDC5 is a metabolic checkpoint regulator in the B cell AA-mTORC1 pathway
Immunometabolism is a rapidly developing field that is central to understanding the homeostatic maintenance and induction of immune responses. Naïve B cells rest in quiescent states until antigen (Ag) is encountered, which simultaneously triggers a metabolic switch enabling enhanced growth, …
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B Cell Receptor Signalng in Germinal Centers
<p>Germinal centers (GC) are sites of B cell clonal expansion, diversification, and antibody affinity selection. This process is limited and directed by T follicular helper cells that provide helper signals to B cells that endocytose, process, and present cognate antigens in proportion to receptor …