Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Axl receptor tyrosine kinase"”.
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The Soluble Form of the Axl Receptor Tyrosine Kinase
The present investigation focus on the receptor Axl, which is a member of the receptor tyrosine kinase family. Axl is activated by the ligand Gas6 inducing cell growth and proliferation, but also regulate inflammation and vascular homeostasis. The Axl receptor can be cleaved outside the membrane, …
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Molecular Players in Lupus: Leads from Proteomic Screens
… pathogenesis. We have discovered that soluble Axl receptor tyrosine kinase, the Wnt/β-catenin pathway-related factors, and rare fibrinogen alpha chain variant A-α-E are elevated in the serum of patients with SLE. Here I explore these factors and their contributions to disease. I find that Axl …
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The Role of Axl and Axl-like Proteins in Murine Spermatogenesis
Mice lacking the Axl receptor tyrosine kinase (RTK) and its family members exhibit detrimental effects on their reproductive ability. AXL is localized to Sertoli cells, which are the major nurturing cells in the seminiferous epithelium. A sequence homology search identified an uncharacterized …
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Axl RTK and microRNAs in urogenital cancers
… thesis is based on four projects focused on the Axl receptor tyrosine kinase (RTK) and microRNAs in clear cell renal cell carcinoma (ccRCC) and in prostate cancer (PCa). Paper I focuses on differentially expressed microRNAs in ccRCC. We used bioinformatics methods to identify candidate microRNAs …