Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Autonomic neurons"”.
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The role of autonomic neurons in the pathegenesis of herpes simplex virus infection
… investigated, especially with in sensory neurons. Another component of the peripheral nervous system (PNS), autonomic neurons, were also known to be infected with HSV productively and latently, but largely ignored because of the assumption that there is no difference in the pathogenesis of …
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From Entry to Dysfunction: SARS-CoV-2 Neuropathogenesis in Peripheral Sensory and Autonomic Neurons and Its Implications
… sustentacular cells and olfactory sensory neurons in the nasal neuroepithelium, enters the olfactory bulb, and spreads throughout the brain. Autopsy studies later suggested that viral entry is also mediated by failure of the blood brain barrier due to inflammation. Missing from these …
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Stress hormones epinephrine and corticosterone modulate herpes simplex virus 1 and 2 productive infection and reactivation primarily in sympathetic, not sensory, neurons
… infect and establish latency in peripheral neurons, from which they can reactivate to cause recurrent disease throughout the life of the host. Stress is associated with exacerbation of clinical symptoms and induction of recurrences in humans and animal models. The viruses preferentially …
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Systematic Co-Culture of IPSC-CM and IPSC-AN Promote Co-Maturation In Vitro
… function. In native heart muscle, sympathetic neurons (SN) and parasympathetic neurons (PSN) modulate the beat rate of cardiomyocytes (CM) to maintain homeostasis. Pluripotent stem cells can differentiate into CM, but differentiated CMs are fetal-like, with a high beat rate, and lack organized …
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Differential regulation of herpes simplex virus-1 and herpes simplex virus-2 during latency and post reactivation in response to stress hormones and nerve trauma in primary adult sensory and sympathetic neurons
… establishment of lifelong latency in sensory and autonomic neurons of the peripheral nervous system that innervate the site of infection. Any cellular stress trigger, ranging from external stimuli such as UV radiation or nerve injury to psychological and physiological stress, can reactivate HSV …
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Neuroscience tools in novel contexts: developing thermogenetics in Drosophila and decoding autonomic activity in mouse major pelvic ganglion
… sensitive. When expressed in Drosophila motor neurons, we observe temperature dependent increases in the frequency and intensity of calcium fluorescence signals measured using a genetically encoded calcium indicator, GCaMP6f. We also show that activation of Gr28bD is sufficient to elicit …