Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Autografts"”.
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Factors Affecting Anterior Knee Pain in Post-ACLR Comparing Patellar Tendon and Hamstring Tendon Autografts
… patellar tendon (PT) and hamstring tendon (HT) autografts. PT autografts have been blamed for chronic anterior knee pain (AKP) and extensor mechanism deficits. This study compared the PT and HT autografts and their impact on AKP in subjects who underwent anterior cruciate ligament reconstruction …
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Anterior Cruciate Ligament Reconstruction; Randomized Trials, Register Studies and Experimental Analysis of Knee Laxity
… (BPTB) or hamstring tendon (HS) autografts was analyzed and knee laxity was compared between the study groups on multiple follow-up occasions. Furthermore, the radiographic findings in terms of degenerative changes were compared. There were no significant differences in the mean …
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A multiscale mechanobiological investigation of scaffold designs for bone tissue engineering
… and reconstruction to ensure proper healing. Autografts, bone grafts taken from elsewhere in the patient's skeleton, are considered the gold standard for treatment; however, autografts are limited in supply, and harvesting them can lead to infection, loss of function, and persistent pain. …
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In situ bioprinting of the skin
… burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and some require a lengthy preparation time, making them unusable in severe cases that require prompt and aggressive measures to maintain the lives of wounded patients. …
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Design of a novel anterior cruciate ligament prosthesis
… standard is currently represented by tendon autografts which, however, result in considerable donor site morbidity. An ideal solution would be to use effective, off-the-shelf permanent prostheses: however, all such devices proposed to date have proved highly disappointing, because of poor …
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Extrusion and evaluation of degradation rate and porosity of small diameter collagen tubes
The limited availability of autografts and failure of small diameter synthetic vascular grafts has stimulated continuing efforts to develop small diameter vascular grafts based on natural materials. The small diameter collagen tubes were extruded using bovine collagen type I. The biodegradation …
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Evaluation of Non-functionalized Single Walled Carbon Nanotubes Composites for Bone Tissue Engineering
… these defects have been repaired by using autografts and allografts. Autografts have set the gold standard for clinical bone repair because of their osteoconductivity, osteoinductivity and osteogenicity. Nevertheless, the application of autografts is limited because of donor availability …
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Innovative Apatite/Bioactive Glass-based materials for biomedical applications
… materials as alternatives to allo- and autografts, due to the drawbacks associated with the employment of the latter ones (as for instance, transmission complications as well as immunological rejection and morbidity). Scientific research focused on synthetic bone graft displaying …
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An alginate hydrogel matrix for the localised delivery of a fibroblast/ keratinocyte co-culture to expedite wound healing
… for effective alternative skin replacements to autografts, allografts and xenografts. In this thesis a bi-layer skin graft was developed by encapsulation of fibroblasts in calcium-alginate hydrogel and culture of keratinocytes on the surface. Initially, the use of 5% and 2% w/v alginate …
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Polypyrrole : an interactive substrate for bone regeneration
Current methods of bone repair rely on autografts (bone from a donor site) and allografts (bone from human cadaver). However, these methods are plagued with disadvantages. There is a clear and urgent need to provide alternatives for regenerating and repairing bone. Bone is known to be one of the …
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Apatite-polymer composites for the controlled delivery of bone morphogenetic proteins
… involves the implantation of a bone graft. Autografts, which are harvested from the patient's own body, are associated with problems of limited availability and surgical morbidity. The use of allografts obtained from donors is also not desirable due to the risks of disease transmission and …
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THE OUTCOME OF MAXILLARY SINUS FLOOR AUGMENTATION WITH RECOMBINANT HUMAN BONE MORPHOGENIC PROTEIN 2 VERSUS CONVENTIONAL SINUS GRAFTING PROCEDURES: A SYSTEMATIC REVIEW
… utilizing other bone grafting materials, such as autografts, allografts, and xenografts. Materials and methods: A search of 3 electronic databases, including PubMed/MEDLINE, EMBASE, Cochran Library Central, and a hand search for peer- reviewed journal relevant articles were performed. Relevant …
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Application of a Periosteum-bone Allograft for Healing of Segmental Bone Defects
Whole bone allografts or autografts are commonly applied surgically to repair approximately 2.2 million segmental bone defects annually caused by trauma or bone tumor resection worldwide.[1] However, about 15-40% of these cases result in unsuccessful healing because of a persistent gap or nonunion …
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Controlling Tissue Matrix Assembly of Human Mesenchymal Stem Cells toward Engineering Native-like Bone, Cartilage, and Osteochondral Grafts
… of allografts, and complications from harvesting autografts. The successfully engineered grafts must exhibit biological and structural function similar to that of native tissue in order to withstand physiological conditions and integrate into surrounding tissues. In this dissertation, the ability …
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Alternative strategies to incorporate biomolecules within electrospun meshes for tissue enginering
… of ACL rupture consists of reconstruction with autografts or allografts. However, the limitations associated with these grafts have prompted interest in tissue engineered solutions that combine cells, scaffolds and stimuli to facilitate ACL regeneration. This thesis describes a ligament tissue …
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Olfactory progenitor cell transplantation into the mammalian inner ear
… cells that may serve as either homografts or autografts. The feasibility of ONSs to survive and integrate into a mammalian cochlea in vivo was assessed. The ONSs were isolated as a crude fraction from the olfactory epithelium of P1 to P3 day old swiss webster mouse pups, ubiquitously …
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Modification of mineralized collagen scaffolds to overcome challenges of craniomaxillofacial bone repair
… strategies to repair these defects involve autografts, or bone from the patient’s own body, but this bone is in limited supply and can cause donor site morbidity. Biomaterial strategies have focused on the use of engineering materials such as metals, ceramics, and polymers to regenerate …
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Natural Polymeric Carriers for Local Delivery of Therapeutic Agents to Promote Enhanced Bone Regeneration
… to be a successful clinical alternative to autografts in promoting bone regeneration. While collagen rhBMP-2 carriers have shown robust regenerative capabilities, adverse side effects such as ectopic bone growth are likely caused by a burst release of supraphysiological levels of rhBMP-2 …
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Preosteoblast Behavior on a Synthetic Calcium Phosphate Scaffold Coated with Cell Derived Matrix
… construct can provide benefits over the common autografts and allografts currently used. Calcium phosphate (CaP) materials offer high biocompatibility and chemical similarity to natural bone tissue. Biodegradable beta-tricalcium phosphate (β-TCP) scaffolds with an interconnected porous network …
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