Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Atrial appendage"”.
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Comparison of Apixaban and left atrial appendage exclusion device (Watchman) in preventing stroke and systemic embolism in atrial fibrillation patients
<p>Atrial fibrillation is a cardiac arrhythmia associated with increased risk of stroke and systemic embolism. Apixaban, an oral anticoagulant, and the Watchman, a left atrial appendage closure device, are the currently used therapeutic treatments for the prevention of stroke and systemic embolism …
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Universal Atrial Coordinate (UAC) for Wall Motion Deep Learning
Atrial fibrillation (AF), the most common persistent arrhythmia, increases stroke risk through altered left atrial (LA) wall motion and blood stagnation in the left atrial appendage (LAA). Standard scores like CHA₂DS₂-VASc overlook patient-specific motion patterns, while AF's episodic nature and …
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Multifunctional soft robotic devices and cardiac benchtop models for improved therapy delivery and development
… of benchtop models of the left atrium and left atrial appendage that enable device testing, development, and procedural training, and replicate (patho)physiological hemodynamics and motion. Taken together, this thesis research aims to create new therapeutic approaches that allow for …
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The electrophysiological and molecular effects of chronic beta-adrenoceptor antagonist therapy on human atrium
… is associated with prolongation of the atrial cell action potential duration (APD), potentially contributing to the ability of these drugs to prevent atrial fibrillation (AF). The mechanisms underlying this APD prolongation are not fully understood but may involve pharmacological …
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Four-Dimensional Cardiac Magnetic Resonance Analysis in Patients with Atrial Fibrillation
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by disorganized electrical activity leading to irregular contractions and impaired cardiac output. AF significantly elevates the risk of thromboembolic stroke, primarily due to thrombus formation in the left atrium (LA) and left …
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The electrophysiological effects of Endothelin-1 in human atrial myocytes
… is associated with an increased incidence of atrial fibrillation (AF) and elevated levels of catecholamines and endothelin-1 (ET-1), each of which affects the atrial L-type calcium current (ICaL) and consequently action potentials. Hypotheses: ET-1 modulates the effects of isoproterenol (ISO) …
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Quality of life, symptoms and experiences of patients with an elevated body mass index undergoing catheter ablation for atrial fibrillation
… body mass index undergoing catheter ablation for atrial fibrillation Background Atrial fibrillation (AF) is the most common arrhythmia seen in clinical practice. Previous studies have demonstrated that AF may result in high symptom burden and a reduced quality of life (QoL). Rhythm control in the …
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Regional Mechanical Properties and Microstructure of Ovine Heart Chambers
… of the left and right ventricles, atria, and appendages underwent biaxial mechanical testing. A Fung-type strain energy function was used to fit the experimental data. Tissue behavior was quantified based on the magnitude of strain energy, as an indicator of tissue stiffness, at equibiaxial …