Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 103 for “"Atomic resolution"”.
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Real-time atomic resolution dynamics of glass surfaces
… be gained by imaging studies of glasses at the atomic scale. This thesis employs the atomic resolution capabilities of scanning tunneling microscopy (STM) to study glass surfaces in real-time. Initial experiments on metallic glass surfaces discovered localized two-state dynamics of atomic …
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Atomic resolution studies of oxide superlattices and ultrathin films
… between the interfacial thin film oxide atomic structure and its properties, atomic scale characterization is required. Transmission electron microscopy (TEM) offers the ability to study interfaces of films at high resolution. Scanning transmission electron microscopy (STEM) allows for …
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Structural and chemical characterization of complex nanomaterials at atomic resolution
… and high-energy X-ray diffraction (XRD). Atomically resolved micrographs provide significant insight into the differences in crystallinity and metal-atom bonding between Pt and Pd. The apparent structural dichotomy between Pt and Pd was extended to studying the differences in nanostructure …
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Multi-Dimensional Dopant Profiling With Atomic Resolution by Scanning Tunneling Microscopy
… profiles were extracted from CITS data with 5A resolution. Moreover, the N and P type dopant induced features were observed in filled state and empty state STM images. The donor (Arsenic) induced feature appears as a protrusion in both the filled and empty state images, while the acceptor …
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Dynamic imaging of nanoparticles on femtoseconds to minutes time scale at atomic resolution
… 40 years since its conception, the excellent atomic resolution of the scanning tunneling microscope (STM) continues to be excavated to develop single-molecule techniques. In the last 20 years, our group has developed and improved the single-molecule absorption scanning tunneling microscopy …
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Theoretical and computational investigations into structure-function relationships of biomolecular machines at atomic resolution
… Despite intense research efforts, the atomic-level mechanism transmitting other form of energy into mechanical force is still unclear. Molecular dynamics simulations, though capable of providing atomic details, are limited in the study of molecular machines owing to the challenge that …
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Molecular Modeling: Elucidation of Structure/Function Relationships of Proteins and DNA at the Atomic Resolution
… molecules, current technology cannot yet monitor atomic fluctuations at relevant time scales. Theoretical computational simulations are able to model the appropriate interactions at atomic resolution. Computational techniques have become widely used for identifying interactions in biological …
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Solution structure and dynamics of myoglobin and its mutants
… structure of sperm whale myoglobin, with atomic resolution is obtained by using nuclear magnetic resonance spectroscopy (NMR).
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Transmission Electron Microscopy Of Structural Disorder In Two-Dimensional Materials
… the structure and properties of individual atomic features. Second, these studies enable the development of new 2D materials and devices with precisely tailored optical, electronic, and mechanical properties. The experiments presented in this thesis show the first atomic-resolution images of …
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Voltage-Gating Mechanism in Potassium Channels
… channel from rat brain, provided the first atomic-resolution structure of a voltage-gated potassium channel, in which the ion conduction gate is open. The studies presented in this dissertation use molecular dynamics simulations to investigate the ion permeation, as well as the gating …
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Voltage-Gating Mechanism in Potassium Channels
… channel from rat brain, provided the first atomic-resolution structure of a voltage-gated potassium channel, in which the ion conduction gate is open. The studies presented in this dissertation use molecular dynamics simulations to investigate the ion permeation, as well as the gating …
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Fundamental efforts for improving the sensitivity of magnetic resonance force microscopy
… rapid access to macromolecular structures at the atomic resolution. As of 2011, a general method for rapid rendering of macromolecular and cellular structures with atomic resolution represents both a major challenge and a major need in science. Such a method would prove all the more valuable to …
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Structural Studies of Lipid-Bound Apolipoprotein A-I and Nanodisc-Embedded Cyp3A4 by SSNMR
… NMR and x-ray crystallography in solving atomic-resolution structures of these proteins. Work presented here focused on development of the Nanodisc platform for structural studies of membrane proteins using solid-state NMR (SSNMR).
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Scanning tunneling microscopy of silicon(100) 2 x 1
… have been prepared and imaged with the STM. Atomic resolution images probing both the filled states and empty states indicate that the surface consists of statically buckled dimer rows.
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Engineering nitrilases for enhanced thermostability
… and single-particle analysis. In this study, atomic resolution structures of wild-type CynDpum and its variant CynDpum (Q86R/H305K/H308K/H323K) were employed to predict, using empirical force fields, the change in Gibb's free energy resulting from mutating each amino acid in the atomic …
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Design and Fabrication of a Nanocantilever for High-Speed Force Microscopy
The atomic force microscope (AFM) has become an important tool in many fields ranging from materials science to biology. The central component of the AFM is a probe consisting of a soft cantilever to which a sharp tip is attached. By scanning the probe over the surface of a sample and measuring …
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Proteins Inside Cells and On the Surface of Membranes: Developing Three Dimensional In-Cell NMR and Structural Characterization of a Trimeric Membrane Proximal External Region Construct from HIV-1 gp41
… by studying the components of those processes at atomic resolution. Major advancements in technology and methodology have been made that continue to improve our ability to determine atomic resolution structures of proteins. These advancements have also enabled new ways to study difficult protein …
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Computational Techniques Applied to RNA Structures and Bacterial Genomes
… is especially true for studies associated with atomic resolution structures and/or NextGen sequencing. In this dissertation, three separate studies are described in which modern computational methodologies play a key role. The first case is a model system that seeks to understand how complexity …
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