Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Atg14L"”.
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Biochemical and Genetic Studies of Beclin 1 Function in Autophagy
… three novel Beclin 1 interaction proteins Atg14L (yeast Atg14-like), Rubicon (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein) and Nrbf2 were identified from mouse tissues. Gel filtration and co-immunoprecipitation show that these proteins co-exist in one large …
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Activation of lipid kinase VPS34 by Rab GTPases
… Complex I consists of VPS34, VPS15, Beclin 1 and ATG14L, whereas complex II contains UVRAG instead of ATG14L. VPS34 complex activity is regulated by membrane properties and by members of the Rab family of small G proteins, which are important for orchestrating intracellular vesicle sorting and …
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Cryo-EM structural exploration of human VPS34 complexes and their activation by RAB GTPases and NRBF2
… and consists of VPS34, VPS15, Beclin1, and ATG14L. In addition, complex I has a tightly bound fifth subunit NRBF2, although its effect on the primary role of complex I is not clear. Complex II has a role in endocytic sorting and contains the same subunits, except the ATG14L is replaced by …