Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Astrocyte activity"”.
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Silencing ITGB3 in Astrocytes
Astrocytes are brain cells that provide support to neurons, brain tissue structure, and can respond to brain injury. After traumatic brain injury (TBI), these cells can become reactive, changing their behavior, structure, and role as they migrate towards the injury site and form glial scars that …
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Probing the Mechanisms of Reinforcement Learning: Reinforcement Learning, Ventral Striatal Astrocytes, and the Dynamic Coordination of Information Seeking with Learning
… In the first chapter, we examined the role of astrocytes in reinforcement learning, and in the second, we investigated human information seeking during reinforcement learning. Neurons in the human and animal brain have been known to support value-based decision-making and reinforcement learning …
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Mechanisms of Astrocyte Contribution to Bortezomib-Induced Peripheral Neuropathy
… injury models have shown activation of both astrocytes and microglia following insult, research in other CIPN models has shown astrocytic activation in the absence of microglial activation. The central hypothesis of this dissertation is that the activity of astrocytes is correlated with …
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The role of estradiol in astrocyte and neuron communication
… longer considered passive players in the brain, astrocytes are now appreciated for their active role in neural communication. The “tripartite synapse” depicts the bidirectional communication between the presynaptic, postsynaptic neuron and the neighboring astrocyte. An important characteristic of …
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Astrocyte-mediated immune modulation during mycobacterial infection
… prime resident immune-effector cells in the CNS; astrocytes however also regulate innate and adaptive immunity in CNS disease and injury. Astrocytes play a progressive role in maintaining the structural and functional integrity of the CNS while supporting neuronal function and participating in …
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Automated Analysis of Astrocyte Activities from Large-scale Time-lapse Microscopic Imaging Data
… protein sensors enables the recording of astrocyte activities on a large population of cells over a long-time period in vivo. Existing tools cannot fully characterize these activities, both within single cells and at the population-level, because of the insufficiency of current …