Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Astroctyes"”.
-
Prodrug Approach to Improve Oral and Brain Absorption of HIV Protease Inhibitor, Lopinavir
… rates across Rif-RBE4 cocultured with astroctyes relative to LPV. This result demonstrates that prodrugs may produce higher permability rates across blood-brain interfaces relative to LPV. Brain absorption of prodrugs was also higher compared to LPV. Importantly, prodrugs were able to …
-
Regulation of STAT-3 and STAT-6 by Transient Oxidative Stress in Rat Brain Astrocytes
… stress conditions using cultured rat brain astroctyes. The present study has shown that individual STAT proteins are differently regulated to H2O2-mediated oxidative stress. Fistly I report that H2O2 induced a decrease in the steady state level of STAT-3 phosphorylation by SHP-2 activation …
-
Characterizing Changes in the Brain During Hydrocephalic Development and Exploring Potential Treatment Strategies
A neurological disorder, hydrocephalus, has an estimated global pediatric prevalence of 380,000 new cases each year [1]. It is a family of diseases that can occur at any age when cerebrospinal fluid builds up within the ventricles of the brain. Thus, the only available treatments are surgical, …