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Showing 1 to 6 of 6 for “"Aspalathin"”.
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The effect of Aspalathin on Doxorubicin-induced Cardiotoxicity
… of chronic diseases. Of particular interest is aspalathin, a plant polyphenol with known antioxidant properties. Aim: This study aimed to investigate the potential use of aspalathin, a dihydrochalcone C-glycoside, in alleviating Doxorubicin-induced cardiotoxicity in an in vitro H9c2 cardio …
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An in vitro and in vivo hepatotoxicity study of an aspalathin- rich green rooibos extract
… or drug-herb interactions. Flavonoids of aspalathin-rich green Rooibos extract (GRT) present many therapeutic properties that reduce the risk of developing cardiovascular diseases. However, there is a gap in literature regarding the efficacy or safety of this particular extract on the …
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A study of the protective effects of an aspalathin enriched green rooibos extract on experimentally induced hepatic steatosis
… in rodents. This study will establish if an aspalathin rich green rooibos extract (Afriplex GRT™) is able to modulate or prevent the excessive fat accumulation in experimental models of NAFLD. Aim: The aim of the study was to assess the modulatory effect of GRT extract in in vitro and in vivo …
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Assessment of chemical markers as surrogates for efficacy and safety of Rooibos extracts
… focus drawn to the dihydrochalcone C-glucoside, aspalathin, which has displayed antidiabetic effects in vitro and in vivo. METHODS Two ethanol-based (80% and 60% ethanol) and aqueous extracts were prepared from ten randomly selected plant batches of green rooibos. HPLC-DAD analysis was performed …
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The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
… gallate (EGCG, from green tea) and aspalathin (from green rooibos), are held as primarily responsible for their health benefits. These flavonoids are known antioxidants that can interact with proteins, carbohydrates and fats, making them bioactive compounds of interest to health …
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The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
… the main antioxidant activity is attributed to aspalathin. Our underlining hypothesis is that the antioxidants in an aqueous rooibos extract may therefore protect against the potential oxidant damaging effects of alcohol on the BBB. Cells were exposed for 24hrs to selected concentrations of EtOH …