Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 15 of 15 for “"Aseptic loosening"”.
-
Aseptic loosening around total hip and knee arthroplasty is linked to plasma microRNA
… end-stage degenerative joint diseases. However, aseptic loosening is still a major cause of prosthesis failure, leading to revision surgery. The pathophysiology of aseptic loosening begins with debris particles being generated as the implants wear over time. These microparticles cause osteolysis …
-
Development of Precision 3D-Printed Medical Implants
… for bone regeneration surgeries. Additionally, aseptic loosening, a common implant failure cause, necessitates arthroplasty revisions. Metal 3D printing enables complex porous implants that enhance osseointegration, reducing aseptic loosening risks. Furthermore, in this research, the osteogenic …
-
IMPLANT MATERIAL FUNCTIONALIZATION TO ENHANCE BIOACTIVITY IN ORTHOPAEDICS
… for the failure of these implants is due to aseptic loosening. The success of implants is highly dependent on firm bonding or fixation of implant biomaterial to bone, for optimal function and lastingness. Thus the aim of this thesis is to develop orthopaedic implant materials with enhanced …
-
Knee Balance Assessment During Cementation Is Detrimental to Initial TKA Tibial Tray Fixation
… in implant design and cement technique, aseptic tibial loosening remains the primary cause of revision after cemented total knee arthroplasty (TKA) [1]. While the mechanisms of tibial loosening are multifactorial, previous research has shown that third-generation cement techniques, …
-
Osseointegration potential for heat treated 3D Ti6Al4V scaffolds seeded with mysenchymal stem cells in vitro
Aseptic loosening of artificial joints occurs due to the loss of implant fixation. By implementing a 3D porous structure at the bone-implant interface, the ingrowth of bone will permit better and stronger interlocking of the implant to prevent loosening. In this study, it is hypothesized that the …
-
Acetabular Component Migration Following Revision Total Hip Replacement
… component after total hip replacement (THR) is loosening. Identifying a surrogate, such as early migration, that could predict the long-term performance of revision acetabular components and techniques is important given the introduction of new implants and techniques. Radiostereometric Analysis …
-
A qualitative holographic study of hemipelvic and acetabular deformation caused by different hip prostheses
Aseptic loosening of the components is probably the most common long-term complication resulting in failure of Total Hip Arthroplasty. The mechanical behaviour of bone under load is one of the contributory causes of loosening encountered at the prosthesis/cement/bone interface. The present study …
-
Effects of select fluids on the friction of metal-on-polyethylene joint replacement surfaces
… that ultimately leads to osteolysis and aseptic loosening. Although research in the materials selection and design of TJA components is continually advancing, one of the major intrinsic components that affect the tribological response in joints is overlooked. In particular, the properties …
-
The Fc Orth (SA) final examination The short-term outcome of hip revision arthroplasty with Trabecular Metal™ components and augments
… errors. The indications for revision were aseptic loosening 67 (58.6%), septic loosening 11 (9.5%), liner wear 18 (15.5%), periprosthetic fracture five (4.3%), other 15 (13%). Conclusion: In our institution, Trabecular Metal™ revisions had a 18.7% early failure rate due to technical error. …
-
Morphology and Localisation of Patient Hip Replacement-Derived Debris and Hip Prostheses Materials in Macrophages
… relieve pain and restore mobility for patients, aseptic loosening is still the most common cause for revision surgery. It is thought there is a contribution from both the sensitivity to the debris produced by implant wear as well as the macrophage-mediated response, producing pro-inflammatory …
-
Characterization and computational modelling of acrylic bone cement polymerisation
… the weak link in the joint replacement system. Aseptic loosening is cited as the cause for the majority of revision operations and cement degradation has been shown to be a contributor to the loosening process. In-vivo, cement is subject to cyclic loads and these are the primary cause of cement …
-
Investigation of a heirarchical collagen scaffold/3D printed lattice structure designed for use in total knee replacements
Aseptic loosening is a common cause of late-stage failure in total knee replacement (TKR) surgery. This multifactorial condition is exacerbated by stress shielding and micromotion at the bone/implant interface. Stress shielding can be reduced using implant materials with a similar modulus to that …
-
Failure of Primary Total Knee Arthroplasty: Establishing a Baseline for Retrieval Analysis Using Well-Functioning Necropsy Specimens
… suboptimal outcomes, such as unexplained pain or aseptic loosening of the implant components necessitating revision of the index procedure. The understanding of the exact etiology of these suboptimal outcomes of primary TKA is in its infancy. In order to elucidate the etiology of failure in …
-
Development And Application Of Biomimetic Electrospun Nanofibers In Total Joint Replacement
… are the two main causes of implant failure and loosening. There is a critical need for orthopedic implants that promote rapid osseointegration and prevent bacterial colonization, particularly when placed in bone compromised by disease or physiology of the patients. A better understanding of the …
-
ΚΡΙΤΗΡΙΑ ΙΞΩΔΟΕΛΑΣΤΙΚΗΣ ΣΥΖΕΥΞΗΣ ΜΑΚΡΩΝ ΟΣΤΩΝ ΚΑΙ ΟΣΤΙΚΟΥ ΤΣΙΜΕΝΤΟΥ
THE REPORTED FAILURE OF ENDOPROSTHESES, WHERE BONE CEMENT IS USED, IS A RESULT OF A SERIES OF INTERACTIONS BETWEEN BIOLOGICAL AND MECHANICAL FACTORS. A FACTORWHICH PLAYS A SIGNIFICANT ROLE IN THE DEVELOPMENT AND PROPAGATION OF MICROCRACKS, BETWEEN BONE AND BONE-CEMENT, IS THE UNSUITABLE MATCHING OF …