Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Artificial Cells"”.
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Molecular communication between artificial cells
… engineering has been widely used to reprogram cells for a variety of purposes, suggesting a wide range of possible applications in industrial and academic research. Although the techniques available are very well established, the mechanisms of cellular life are not completely understood. …
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Engineering Internal and External Molecular Pathways in Artificial Cells
Bottom-up synthetic biology aims to engineer artificial systems exhibiting biomimetic struc- ture and functionality from the rational combination of molecular and nanoscale elements. These systems often take the form of artificial cells: micron-scale, cell-like constructs that display advanced …
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Cell-free expression systems for the construction of artificial cells
Cell-free expression systems are widely used to synthesize proteins for subsequent further characterization, to manufacture potentially useful commercial end products, and to construct cellular mimics in the laboratory. The first part of the thesis explores the feasibility of preparing two of the …
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DNA-based Artificial Mimics of Cell-surface Machinery
The plasma membrane of cells has evolved to mediate a broad array of functionalities critical to life, such as molecular trafficking, signal transduction, motility, adhesion and communication. These functionalities are often reliant on highly sophisticated membrane-anchored nano-machines, and …
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A Bottom-Up Approach to Building an Artificial Cell by Self-Assembly
… advances now allow the formation of minimal or artificial cells composed of a minimum number of components, capable of performing specific functions. New developments contributing to the complexity of artificial cells or making their design more cell-like increases the number of possible …
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Suspension, yielding, microstructure and applications of bacterial cellulose dispersion
… and protection, and potentially a framework for artificial cells.
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Uncovering Structure-Property Relations in Biomimetic Lipid Membranes with Molecular Additives
… to meet the diverse functional needs of cells. These bilayers must strike a delicate balance: they need to be sufficiently rigid to act as protective barriers, yet fluid enough to facilitate the diffusion of proteins and molecular clusters crucial for various biological processes. Owing …
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Programmable Assembly of Elastin-like Polypeptides Within Droplet Microenvironments
… gene expression within droplet-based protocells. Taken together, this body of work offers new insights into (1) our understanding of the genetic to molecular to macroscale relationships encoding naturally occurring intrinsically disordered protein assemblies, (2) the design rules of these …
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Compositional Control of Phase-Separated Cellular Bodies
… proteins and RNA. \textit{In vitro} and in cells these scaffold molecules form phase separated liquid droplets that are strongly enriched with the scaffold molecules. Analytical theories of polymerization suggest the resulting second phase contains large polymers of the multivalent …