Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 190 for “"Articular Cartilage"”.
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Diffusional Properties of Articular Cartilage
Articular cartilage is the connective tissue that lines joints and provides a smooth surface for articulation and shock absorption. Osteoarthritis, the progressive degeneration of cartilage, is a painful, debilitating, and widespread disease, affecting 70% of people over 65. Because cartilage is …
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Towards understanding multiscale articular cartilage mechanics
… of the chondrocytes, the sole cell type in articular cartilage, is of high importance to developing and maintaining a healthy tissue state. Mechanical cues play a major role in the regulation of many cellular functions. The dominant mechanics experienced by chondrocytes are translated from …
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Inhibition of metalloproteinases in articular cartilage
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1995.
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Electrokinetic evaluation of human articular cartilage
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1995.
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Biotribology: articular cartilage friction, wear, and lubrication
… and refined techniques for the in vitro study of cartilage-on-cartilage friction, deformation, and wear. Preliminary results of in vitro cartilage-on- cartilage experiments with emphasis on wear and biochemistry are presented. Cartilage-bone specimens were obtained from the stifle joints of steers …
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Contact mechanics modelling of articular cartilage and applications
Osteoarthritis (OA) is a degenerative disease of articular cartilage. The normal cartilage is known to be an excellent bearing material with remarkable lubricating properties and very low frictional co-efficient and wear and generally survives the lifetime of a person. The contact mechanics of the …
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Hysteretic response of articular cartilage to cyclic loading
… investigates the phenomenon of hysteresis in cartilage experimentally. The presence of a hysteresis loop in cartilage indicates energy loss, thereby signaling degradation of cartilage leading to osteoarthritis. Although hysteresis in ligaments and tendons has been studied to a great extent, …
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Knee Osteoarthritis: gagCEST MR Imaging of Articular Cartilage
… health problem that involves the disorder of articular cartilage. Until now, there is no effective cure for it. However, beginning treatments and therapies at an early stage can help in preventing further disease progression.It has been reported that the loss of glycosaminoglycan (GAG) in …
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Joint contact modelling of articular cartilage in synovial joints
… high contact forces and stresses. However, cartilage shows remarkable lubricating and wear properties, and survives the lifetime of a person. Biphasic lubrication based on the principle of fluid load support has provided an explanation for this. However, when, the cartilage fails the part or …
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Impact loading and functional tissue engineering of articular cartilage
… two advances for alleviating the problem of articular cartilage degeneration: mitigating degradative changes that follow mechanically induced injuries and growing functional neo-cartilage for diseased tissue replacement. Experiments demonstrate that cartilage subjected to a single, …
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Mechanical Simulation of Articular Cartilage Based on Experimental Results
Recently, a constituent based cartilage growth finite element model (CGFEM) was developed in order to predict articular cartilage (AC) biomechanical properties before and after growth. Previous research has noted limitations in the CGFEM such as model convergence with growth periods greater than 12 …
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Transport studies of chondroitin sulfate disaccharide through articular cartilage
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.
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Electroextraction of proteoglycans from calf articular cartilage in vitro
Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1989.
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Outcome measurement in articular cartilage repair: exploring the patient perspective
… perspective of outcome measurement after articular cartilage repair (ACR) of the knee. The work represents the evolution and development of the author's coherent research programme in this field over a period of 8 years. In 2003 the author conducted a comparative analysis of rehabilitative …
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Experimental and analytical techniques for studying mechanotransduction in articular cartilage
… cells with the full tissue-scale response. Articular cartilage is one such system where the complex extracellular matrix and heterogeneous cell responses make it difficult to understand how chondrocytes respond to injury-inducing strain. In this thesis I will explore the methods I developed …
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Viscoelasticity of Articular Cartilage and Ligament: Constitutive Modeling and Experiments
Articular cartilage and ligament are soft fibrous connective tissues with apparent viscoelastic behavior. An anisotropic visco-hyperelastic constitutive model for these tissues has been proposed in this study based on the short-term and long-term internal variables. The constitutive model was …
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Mechanisms of macromolecular transport through articular cartilage : relevance to loading
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1996.
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Electromechanical dynamics of articular cartilage as it undergoes degenerative changes
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1983.
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