Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Arthropod-Borne Virus"”.
-
Evaluation of arthropod-borne virus recombination potential and phenotype: In vitro and in vivo analysis of flavivirus and alphavirus model systems
… whereby positive sense single stranded RNA viruses exchange segments of genetic information. Recent phylogenetic analyses of naturally occurring recombinant flaviviruses have raised concerns regarding the potential for the emergence of virulent recombinants either post-vaccination or …
-
OROPOUCHE VIRUS DISRUPTION OF HOST CELL FUNCTIONS: PYROPTOSIS INDUCTION AND TRANSCRIPTIONAL SUPPRESSION
Oropouche virus (OROV) is an arthropod-borne virus that infects several species of animals and humans, primarily in Central and South America. Despite being described as a human pathogen more than 60 years ago and of its public health significance, little progress has been made towards describing …
-
Molecular analysis of La Crosse virus transcription and replication in host cells
La Crosse (LAC) virus is an arthropod-borne virus (family Bunyaviridae, genus Orthobunyavirus) transmitted by Aedes triseriatus mosquitoes and is an important cause of pediatric arboviral encephalitis in the United States. Like other arthropod-borne viruses, LAC virus can be very cytolytic in …
-
Characterizing the effect of mutation recombination and reassortment on the genetic diversity of African horse sickness virus genomes
African horse sickness virus (AHSV) is a member of the Orbivirus genus within the Reoviridae family and the aetiological agent for African horse sickness (AHS). It is an arthropod-borne virus transmitted by biting midges belonging to various Culicoides spp. Nine antigenically distinct AHSV (AHSV …
-
Developing a Novel, Safe, and Effective Platform for Generating Flavivirus Vaccines
Viruses in the Flavivirus genus (e.g., Zika, yellow fever, dengue, West Nile, and Japanese encephalitis viruses) are arthropod-borne, globally distributed, and can cause a range of neurological or hemorrhagic diseases. The ongoing epidemics of flaviviral disease consistently demonstrate the need …
-
The Structure and Replication of Semliki Forest Virus, A Mosquito-Borne Animal Virus
<p>Semliki Forest virus is a group A arthropod-borne virus which contains RNA and possesses a lipoprotein envelope. It can be transmitted among animals by mosquitoes in which it multiplies, but its natural host is not known. The virus grows to high titer in a number of types of vertebrate cells in …
-
West Nile virus in Italy: beyond the bird routes
Context: West Nile virus (WNV) is an arthropod-borne virus considered a One Health challenge because of its increasing impact on human and animal health. It is one the most widely distributed viruses of the encephalitic Flaviviruses. It may cause severe neurological symptoms in humans and animals …
-
Population Structure of Yellow Fever Virus: Influence of Viral Diversity on Vaccine Attenuation
Yellow fever virus (YFV) is the prototype of all arthropod-borne viruses, the study of which encompasses some of the landmark paradigm shifts in modern vaccinology. Recently, studies on the lifecycle of RNA viruses have indicated that population structure of these viruses is in many cases complex, …