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Showing 1 to 6 of 6 for “"Arterial input function"”.
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Statistical modeling strategies for estimation of the arterial input function in dynamic positron emission tomography data analysis
… concentration in blood plasma, described by the arterial input function (AIF). Arterial blood sampling is the gold standard for AIF measurement, but is invasive and labour intensive. A number of methods have been proposed to accurately estimate the AIF directly from blood sampling and/or imaging …
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Quantification of cardiac magnetic resonance imaging perfusion in the clinical setting at 3T
… the convolution of a model with the arterial input function (i.e. contrast agent concentration-time curve extracted from the left ventricular cavity) is fitted to the tissue contrast agent concentration-time curve. In contrast to dual bolus DCE-MRI protocols, single bolus protocols …
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Automated perfusion-weighted MRI metrics via localized arterial input functions
… calculates perfusion metrics by defining an arterial input function (AIF) for every voxel in the brain based upon the voxels in close proximity to it. This allows for automated calculation of perfusion metrics, and the localized nature of the AIFs creates an implicit regard for delay and …
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Improved quantification in small animal PET/MR
In translational medicine, complementary functional and morphological imaging techniques are used extensively to observe physiological processes in vivo and to assess structural changes as a result of disease progression. The combination of magnetic resonance imaging (MRI) and positron emission …
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Improved statistical quantitation of dynamic PET scans
… course can be expressed as a convolution between arterial input function (AIF) and the tissue impulse response/residue function. Kinetic analysis is concerned with the estimation of residue and associated physiological parameters such as flow, flux and volume of distribution. Some traditional …
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The analysis of dynamic contrast-enhanced magnetic resonance imaging data: treatment effects, sampling rates and repeatability
… problem of extracting an accurate and precise arterial input function (AIF) is reviewed, as are current proposed solutions. The general principles underlying the implementation of a customised software analysis package for the analysis of DCE-MRI data are described. Data from studies involving …