Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 65 for “"Arterial Wall"”.
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Mechanical properties of arterial wall
… to be correlated with the overstretching of the arterial wall during an angioplasty procedure. It has been proposed that slow balloon inflation results in lower intramural stresses, therefore minimizing vascular injury and restenosis rate. The analysis of the biomechanics of the arterial tissue …
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Low density lipoprotein transport and metabolism in the arterial wall
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1985.
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Lipoprotein Lipase in the Arterial Wall: Regulation by Dietary Fatty Acids
Arterial LDL deposition is a key step in initiating atherosclerosis. Saturated fat (SAT)-enriched diets increase arterial LDL deposition, total and selective LDL-cholesterol uptakes, and arterial lipoprotein lipase (LpL). Because consumption of n-3 fatty acids (FA), such as EPA and DHA, potentially …
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Automatic Arterial Wall Detection and Diameter Tracking Using M-mode Ultrasound
… an algorithm to automatically detect artery wall region and estimate systolic and diastolic lumen diameter of the artery is proposed using ultrasound radio-frequency signals acquired with a single ultrasound transducer in M-mode.Detection of the region containing the artery walls is obtained …
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Computational Analysis and Simulation of the Non-Linear Arterial Wall Dynamics with Application to Abdominal Aortic Aneurysms
North Carolina State University Theses Mechanical and Aerospace Engineering.
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Arterial Wall Hypertrophy and PDGF-A Expression in One-Kidney, One-Clip Hypertension and Angiotensin II Infusion Are Mediated By Elevated Arterial Pressure
… analysis revealed that cross-sectional wall area was correlated with elevated arterial pressure, but not with angiotensin II infusion or AT1 receptor activation. Immunohistochemical analysis indicated that vascular smooth muscle cell hypertrophy, not hyperplasia, contributed to the …
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Modeling and simulation of coronary stents: Intravascular drug delivery and arterial drug distribution
… the specific spatiotemporal drug uptake in the arterial wall. In this work local delivery of a hydrophobic drug from a drug-eluting stent implanted in a coronary artery is investigated using a mathematical model that couples drug diffusion and reversible binding in the arterial wall. The model …
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An investigation of the fluorescence emitted by arterial intimas during irradiation by a XeCl excimer laser
… limited by the unacceptably high rate of vessel wall perforation. To overcome this limitation, fluorescence spectroscopy of arterial wall tissue has been proposed as a technique to discriminate between normal and atherosclerotic arteries and thereby prevent arterial wall perforation during laser …
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Mathematical modeling and simulation of intravascular drug delivery from drug-eluting stents with biodegradable PLGA coating
… pharmacokinetics, and distribution in the arterial wall. A model framework is developed in the first part of the dissertation, where a biodurable stent coating is considered, and the intravascular delivery of a hydrophobic drug from an implanted DES in a coronary artery is mathematically …
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Fluid and structural modeling of the disease-free and atherosclerotic human carotid bifurcation
… build up. Atherosclerosis can also damage the arterial wall and in turn cause the formation of a thrombus that can partially or totally occlude the diseased artery. If the actual vessel is the carotid artery, this often leads to a stroke. The focus of this study is to analyze the blood flow and …
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Aging Effects on Arterial Mechanics and Matrix Remodeling
… cells and extracellular matrix proteins. Passive arterial mechanical behavior is determined by the composition of extracellular matrix proteins, in particular elastin and collagen. Elastin provides reversible elasticity to the large elastic arteries during cyclic loading and dampens the pulsatile …
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Multi-scale quantitative elastography and its application to blood pressure estimation
… are applied to estimate noninvasively the arterial wall stiffness of a vessel as well as blood pressure. Simulation and experimental results are presented that predict the accuracy of the methods. A method is also introduced to eliminate the need for a reference pressure during the …
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Characterization of the Mechanism of PPARγ-Mediated Neointima Formation in Rodents
… ether analog alkyl glycerophosphate (AGP) elicit arterial wall remodeling when applied intralumenally into the uninjured carotid artery. LPA is the ligand of eight GPCRs and the peroxisome proliferator-activated receptor γ (PPARγ). We pursued a gene knockout strategy to identify the LPA receptor …
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Diabete ed ischemia critica degli arti inferiori. Studio del danno della parete arteriosa e del ruolo dell'endotelio circolante nella riparazione tessutale e nella neoangiogenesi
… we sought to establish whether the vascular wall damage, the mature circulating endothelium and the "in situ" neoangiogenesis are related with each other. Design In the peripheral blood of diabetic patients suffering critical ischaemia associated with peripheral artery disease, low levels and …
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Arterial Calcification and the Clinical Implications on Stent Function
For patients with peripheral arterial disease (PAD), endovascular stenting can be a promising therapy that alleviates plaque obstruction and restores blood flow. However, stent fracture is a serious problem and it can lead to vascular complications, including restenosis. Stent fracture can be …
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Remote controlled drug release in drug-eluting stents
… flaws resulting in the restenosis is denying the arterial wall time to heal after implantation due to the sequential drug release. Introducing a novel smart drug delivery system onto stents can enable the release of drug locally in a controlled manner by means of an external ultrasonic stimulus. …
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Numerical Simulation of Unsteady Flows of Physiological Relevance
… of dynamical patterns of pulsating flow, near wall effects, and differential diffusion effects are not well documented. The effect of wall elasticity on the flow has been assumed to be small but no quatification data exist. There are same basic difficulties in studying physiological flow: The …
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Identification of potential clinical indicators of carotid plaque disruption using patient specific finite element modelling
… that the stress distribution within the arterial wall may provide an indicator of atherosclerotic plaque disruption. Many studies have used patient specific finite element models to estimate the stress environment in atherosclerotic plaques, attempting to correlate the magnitude of stress …
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Multiphysics Computational Model of Fluid Flow and Mass Transport in Aneurysm
… with the progression of hypoxia in the arterial wall. The extent that ILT presence reduces oxygen flux to the wall has not been quantified and there is rather a poor understanding of key parameters that can affect thrombus-mediated oxygen transport in AAA. The purpose of this study is to …
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