Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Arterial Tone"”.
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T-type Calcium Channels in Arterial Smooth Muscle: Activity, Regulation and Function
… regulators of excitation-contraction coupling in arterial smooth muscle. Despite evidence of T-type CaV channels in rodent smooth muscle, little is known of their regulation and function. This thesis sought to delineate T-type Ca2+ channels, ascertain if they are regulatory targets of vasoactive …
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CaV3.2 Channels and BKCa-Mediated Feedback in Vascular Smooth Muscle
… vascular T-type Ca2+ channel, CaV3.2, regulates arterial tone by triggering Ca2+ sparks and activating large conductance Ca2+-activated K+ (BKCa) channels. Despite being an integral element of an arterial feedback loop, little is known of its regulation and how key receptors and signaling …
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An Intramural, Tension-modulating Reflex in the Rat Caudal Artery
… was shown to exist between the initial level of tone and the EFS-induced relaxation. It can be concluded that the vascular smooth muscle contains an endogenous hyperpolarization mechanism that regulates initial changes in arterial tone. Higher arterial tension causes the release of NO and another …
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Investigating the Role of Phosphodiesterase 1C in Vascular Smooth Muscle Cell Migration and Invasion
Phenotypic plasticity of human arterial smooth muscle cells (HASMCs) allows them to transition from a “contractile/quiescent” state, in which they regulate arterial tone and blood pressure, to one in which these cells are more “synthetic/activated”. Synthetic/activated HASMCs are migratory and …
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Hemodynamic analysis of flow near cerebral aneurysms: Insight into aneurysm formation and effects of intervention
… in waveform shape as a result of degeneration of arterial tone. It is shown that AFI indeed captures the differences in the waveforms of an older and a younger adult. Fourth, hemodynamic influences on aneurysm stability under realistic physiological conditions are explored, and contrary to what …
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Studies of vascular function in patients with heart failure and either preserved or reduced left ventricular systolic function
… of HF-PSF. Although there are limited data on arterial stiffness in HF-PSF, there have been no studies examining other parameters of vascular function in HF-PSF and vascular function has never been formally compared in cohorts of patients with HF-PSF and heart failure due to reduced LV systolic …
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The role of the muscle metaboreflex in patients with chronic disease
… taken for a pulse wave to travel between two arterial sites, and can be easily and non-invasively measured. It is thought to reflect blood pressure and arterial tone. In a group of healthy subjects, we found that pulse transit time fell with rhythmic handgrip exercise, and post-exercise muscle …
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Exercise, arterial pressure control & systemic O2 tension : implications for post exercise hypotension in hypertension
… condition. 9 pre-hypertensive males, mean arterial pressure (MAP) = 106 ± 5 mmHg (50 ± 10 yr), not on medication, were studied for 6 hours following 30-minutes of cycle exercise at 70% maximal oxygen consumption and following 30-minutes of seated rest. Results demonstrate that moderate …