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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 6 of 6 for “"Argonaute protein"”.

  1. Characterizing the functional role of argonaute protein PIWIL4 in acute myeloid leukemia

    Bamezai, ShivaUniversität Ulm

    ulm-diss Repository record

  2. RNAi-related genes in Toxoplasma gondii.

    Al Riyahi, AhmadUniversity of Windsor2005

    … triggers degradation of homologous transcripts. Argonaute proteins and small interfering RNAs (siRNAs) are the known signature components of the RNAi effector complex, named RNA-induced silencing complex (RISC). Our group previously reported that dsRNA-induced specific gene silencing is …

    windsor Repository record

  3. Restoring and enhancing Argonaute2-catalyzed cleavage

    Chen, Grace RMassachusetts Institute of Technology2018

    … core of the RNA silencing pathway relies on an Argonaute protein in complex with a small RNA. Together, this complex targets transcript RNAs through sequence complementarity to induce the destruction of the transcript RNA either through Argonaute2-mediated slicing or mRNA destabilization and …

    mit Repository record

  4. Characterizing Populations of Non-Coding RNAs in <i>Karenia brevis</i> at Different Times of the Diel Cycle

    Anglin, Scott Boyd2016

    … the small RNAs are too long to be bound be the Argonaute protein, which is a key factor in miRNA synthesis. Cleavage patterns, transcript shape and read alignment patterns resemble a <em>cis</em>-Nat pathway, although it is undetermined whether this leads to siRNAs or an alternate small RNA. The …

    usm Repository record

  5. Studies on the mammalian piRNA pathway in cancer cells

    Keam, SimonUNSW, Sydney2012

    … noncoding RNAs that complex with members of the Argonaute protein family, the Piwi proteins. The Piwi/piRNA pathway is highly conserved in animals and is implicated in spermatogenesis, germline stem cell maintenance, and transposon suppression in the germline. In mammals, the latter occurs via de …

    unsw Repository record

  6. Engineering programmable nucleases for in vivo and in vitro applications

    Xun, GuanhuaUniversity of Illinois at Urbana-Champaign2024

    … repeats (CRISPR) associated nucleases, and Argonaute nucleases (Ago) have revolutionized genome engineering by allowing precise and easy manipulation of genetic material. These reprogrammable nucleases hold immense potential not only for genome editing but also for nucleic acid detection, …

    uiuc Repository record