Global ETD Search
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Showing 1 to 2 of 2 for “"AqB011"”.
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Developing Novel Conservative Treatments For 2 Endometrial Cancer By Targeting Aquaporin-1
… ion channel inhibitors (Bumetanide derivatives AqB011 60 μM-100 μM, 5-HMF, 1mM, 5-PMFC 0.5 mM), and non-specific AQP4 modulators (IMD-0354 0.2 μM, TGN-020 3 μM). A wide range of dose of all drugs were tested and optimal doses causing 50% inhibition of invasion were identified. We found that …
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Pharmacological Modulation of Cancer Migration and Invasion Through Targeting AQP1 Ion and Water Channel Activity
… II, and an aquaporin-1 ion channel blocker AqB011 were used. The circular wound closure assay is an innovative alternative approach for measuring cell migration and was introduced and utilised in this thesis. Cell viability and proliferation was quantified using an alamarBlue assay. Cell …