Global ETD Search
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Showing 1 to 2 of 2 for “"Apremilast"”.
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Novel approaches for ungual and trans-ungual delivery of drugs
… project was to investigate the penetrability of apremilast into and across the nail plate, folloby the preparation of a novel nail lacquer formulation to improve its ungual and trans-ungual permeation for the treatment of nail psoriasis. Dexpanthenol and salicylic acid were found to be the …
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Exploring co-milling as a strategy to improve the dissolution of poorly water-soluble drugs
… between low Tg (fenofibrate) and high Tg (apremilast) drugs. Apremilast, milled below its Tg, exhibited progressive amorphization and supersaturation during dissolution testing. A strong linear correlation between melting point depression and maximum drug concentration (cmax) in vitro (R2 > …