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Showing 1 to 1 of 1 for “"AppNL-G-F Mouse Model"”.

  1. The Emergence of Network Hyperexcitability and Functional Impairment in a Mouse Model of Alzheimer’s Disease

    … of genotype-driven Aβ pathophysiology in a mouse model of AD. To this end, both acute ex vivo hippocampal slices and primary hippocampal cultures derived from humanised AppNL-G-F knock-in mice — which express familial AD mutations that increase the relative expression of pathogenic Aβ42 and …

    cambridge Repository record for The Emergence of Network Hyperexcitability and Functional Impairment in a Mouse Model of Alzheimer’s Disease (opens in a new tab)