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Showing 1 to 7 of 7 for “"Apolipoproteins E"”.
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Die altersabhängige Makuladegeneration : Untersuchung zur genetischen Assoziation des Apolipoproteins E und des Alpha-2-Makroglobulins
Die Arbeit dient der Aufklärung genetischer Ursachen der altersabhängigen Makuladegeneration (AMD) – einer komplexen Erkrankung mit bisher unklarer Ätiologie. Ziel der Arbeit war die Untersuchung einer möglichen Assoziation der AMD mit Polymorphismen in den Genen für Apolipoprotein E (ApoE) und …
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Genetic polymorphism of the human apolipoproteins A and E
… was used to demonstrate the polymorphism of the apolipoproteins E, A-I, A-II and A-IV. Polymorphic forms of apo E were detected after ultracentrifugation of plasma, delipidation of VLDL and isoelectric focusing of the remaining protein. The six common phenotypes, homozygotes E 2/2, E 3/3, E 4/4 …
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ApoE, ApoER2, and the Regulation of Endothelial Cell Function
Cardiovascular disease risk is greater in individuals with the apolipoprotein E (ApoE) allele ApoE4 versus ApoE3, and this is not explained by differences in lipid profiles. A point mutant of the ApoE receptor ApoER2, ApoER2-R952Q, is also associated with greater cardiovascular disease risk, …
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Analysis of Hepatocyte Secretion Pathways: A Case Study on Hepatic Apolipoproteins, Serum Albumin, and Hepatitis C Virus
… of the following cargoes: serum albumin, the apolipoproteins E and B100 (ApoE and ApoB100, respectively, both lipoprotein components, and surrogate markers for these complex macromolecular particles), and HCV, a lipoprotein-associated virus. I propose to combine genetic, biochemical, …
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Apolipoprotein E genotypes and Alzheimer disease in two black population groups
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Regulatory Role of ApoE and Apoer2 in Synaptic Activity: A New Insight into Alzheimer's Disease
Apolipoprotein E (ApoE) genotype is the major genetic modifier of late-onset Alzheimer's disease (AD), the most common neurodegenerative disease in the elderly. By unknown mechanisms, ApoE4 isoform is strongly associated with a substantially earlier age of onset of AD. A synaptic ApoE receptor, …
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ApoE Receptors in Alzheimer's and CNS Function
Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder and the most common form of dementia over age 65. The predominant genetic risk factor for AD is the ε4 allele of apolipoprotein E (ApoE4). Other genes related to lipid metabolism and lipoprotein receptor signaling have …