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Showing 1 to 7 of 7 for “"Apolipoprotein E4"”.

  1. Apolipoprotein E4 and SirT1 Interaction in Alzheimer’s Disease

    Philpot, Brittany Ann1970

    … are still unknown. Εpsilon 4, an allele of apolipoprotein E (ApoE4), is currently the most important risk factor for Alzheimer’s disease. Individuals that inherit two copies of the ApoE ε4 allele have an approximately ten to thirty times increased risk of developing AD in comparison to …

    dominican Repository record

  2. Modeling Developmental, Molecular, and Behavioral Effects of an Apolipoprotein-E4 Fragment on the Embryogenesis of Zebrafish

    McCarthy, Madyson

    boise Repository record

  3. The Development and Implementation of a TMT-SRM Assay for the Validation of Candidate Biomarkers of Alzheimer’s Disease

    O'Brien, DarraghKing's College London2011

    … and non-demented controls. Additionally, apolipoprotein E4 was included in the panel as possession of the apolipoprotein e4 allele is the only unequivocal genetic risk factor for late-onset Alzheimer’s disease and the protein expression of this genetic association may translate as an …

    kings Repository record

  4. Subclinical Atherosclerosis and Cognitive Functioning in a Population-Based Sample

    Rossetti, Heidi Christine2010

    … group as a whole, and in relation to age and ApoE4 allele status. Indirect measures of atherosclerosis (diabetes, hypertension, hypercholesterolemia, abdominal obesity) were also examined. Logistic regression was used to examine the association between direct and indirect measures of subclinical …

    utswmed Repository record

  5. Risk Factors for Postoperative Cognitive Dysfunction in Older Adults Undergoing Major Noncardiac Surgery

    Shoair, Osama2018

    … protein (CRP), and patients who had the apolipoprotein-E4 (ApoE4) allele, as potential inflammatory and genetic biomarkers for POCD, respectively. A nonsurgical control group, that is similar to patients in age, education level, and computer familiarity, was recruited to adjust for …

    vcu Repository record

  6. Characterization and Differences Between Possible and Probable Mild Cognitive Impairment

    Denney, David Austin2010

    … of vascular risk factors and presence of the apolipoprotein element 4 (APOE-4) allele than the Possible MCI patients, who will have higher incidence of these variables than controls. There is also a demographic analysis designed to identify any differences in age, education, and gender between …

    utswmed Repository record

  7. Axonal Damage in Repetitive Concussive Traumatic Brain Injury: Characterization and Contributing Factors

    Bennett, Rachel2014

    … to be developed.</p><p>Last, the contribution of Apolipoprotein E to axonal injury after moderate-severe traumatic brain injury was assessed in a transgenic mouse model carrying three human familial AD mutations (PS1<sub>M146V</sub>, tau<sub>P301L</sub>, and APP<sub>SWE</sub>). The Apolipoprotein …

    wustl Repository record