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Showing 1 to 19 of 19 for “"Apicomplexa"”.
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Charakterisierung und Lokalisation der Toxoplasma gondii Katalase: Peroxisomen in Apicomplexa?
… einzelliger Parasit aus dem Phylum der Apicomplexa. Infektionen des Menschen mit T. gondii verlaufen meist subklinisch. Nach einer Infektion persistiert der Erreger für viele Jahre in Hirn- und Muskelgewebe. Durch Reaktivierung des Erregers, z. B. durch eine Immunschwächekrankheit oder …
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Lysine acetyltransferase Gcn5-B regulates the expression of crucial genes in Toxoplasma and its function is regulated through lysine acetylation
… expression and is a validated drug target of apicomplexan parasites, but little is known about the roles of individual histone modifying enzymes and how they are recruited to target genes. The protozoan parasite Toxoplasma gondii (phylum Apicomplexa) is unusual among invertebrates in …
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Development and characterization of novel toxoplasma gondii inhibitors
… intracellular, protozoan parasite of the phylum Apicomplexa. While the parasite relies on the feline to complete its life-cycle, many mammals can contract the infection. In humans, infection can cause serious illness or death. Treatments currently available are limited by toxicity and …
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Sphingolipids in Toxoplasma gondii; synthesis and scavenging
… currently uncharacterized in T.gondii and other Apicomplexa. In this work the evolutionary origins, function and the cellular localization of this protein were investigated. Further to this, endocytosis assays were also performed on extracellular tachyzoites to investigate the potential of the …
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Soluble expression of plasmodium falciparum glutamine synthetase and three-dimensional structure by single particle reconstruction
[No subject] Malaria infection caused by the apicomplexa pathogen Plasmodium falciparum has a high rate of resistance to existing anti-malarial drugs. The World Health Organisation recommended interventions are unlikely to eliminate the growth of resistance and it would therefore be prudent to …
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Žarnyno Sarcocystis infekcijos paplitimas rudosiose lapėse (Vulpes vulpes) /
… (Vulpes vulpes) Sarcocystis genus belongs to Apicomplexa phylum. These parasites have a two host life cycle. The intermediate host is usually a herbivore and the definitive is a carnivour. The sarcocysts are formed in the muscle tissue and CNS of the intermediate host by asexual reproduction. …
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Sphingolipid synthases of Toxoplasma gondii and other organisms
… intracellular protozoan parasite of the phylum Apicomplexa, and toxoplasmosis is an important disease in immuno-compromised individuals - especially AIDS patients, organ transplant recipients and patients receiving anti-cancer chemotherapy. Toxoplasmosis also has economic importance as it …
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A Molecular Basis for Divergent, Unstable Actin Filaments in Toxoplasma gondii
… is an important parasitic pathogen of the phylum Apicomplexa. Parasite invasion of host cells involves a unique gliding motility mechanism that is dependent on polymerization of parasite actin. However, in non-motile parasites, the majority of actin is monomeric and filaments only assemble upon …
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Dynamics and Fate of the inner Membrane Complex in Apicomplexan Parasites
The eukaryotic phylum apicomplexa encompasses many thousands of parasite species of medical and veterinary importance, including Plasmodium sp. and Toxoplasma gondii. These obligate intracellular parasites survive and replicate within suitable eukaryotic hosts, ultimately rupturing infected cells …
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Funktionelle Charakterisierung antioxidativer Enzyme aus Toxoplasma gondii
Im Stamm Apicomplexa, zu dem der obligat intrazelluläre Parasit Toxoplasma gondii gehört, waren bis zum Beginn dieser Doktorarbeit noch keine Peroxisomen beschrieben, ein in fast allen eukaryontischen Zellen vorkommendes Organell. Das Markerprotein von Peroxisomen ist das Enzym Katalase, welches …
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Gregarine parasitism in dragonfly populations of Central Texas with an assessment of fitness costs in Erythemis simplicicollis.
… and frequently include gregarines (Phylum Apicomplexa) in the gut of the host. Gregarines are ubiquitous protozoan parasites that infect arthropods worldwide. More than 1,600 gregarine species have been described, but only a small percentage of invertebrates have been surveyed for these …
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Development of a Canine Coccidiosis Model and the Anticoccidial Effects of a New Chemotherapeutic Agent
… intracellular parasites belonging to the phylum Apicomplexa. Many coccidia are of medical and veterinary importance such as Cystoisospora species and Toxoplasma gondii. The need to discover new anticoccidial therapies has increased due to development of resistance by the parasite or toxicity …
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In cellulo and biophysical exploration of the role of GGMP residues of Hsp70
… Some Hsp70s of parasites particularly those of apicomplexa are marked by GGMP residues. For example, Plasmodium falciparum Hsp70-1 (PfHsp70-1) which occurs in the cytosol and nucleus harbors seven GGMP repeats on the C terminus upstream of the EEVD motif. The function of GGMP residues of Hsp70 …
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Mining the Genetic Diversity of the Pathogenic Protozoan, Neospora caninum
𝘕𝘦𝘰𝘴𝘱𝘰𝘳𝘢 𝘤𝘢𝘯𝘪𝘯𝘶𝘮 is a cyst-forming apicomplexan parasite, responsible for economic and reproductive losses to cattle industries worldwide, and represents a serious neurological disease in canines. Although discovered over three decades ago, progress towards treatment and control strategies against …
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Inhibition of the Toxoplasma gondii replication by inhibition of the mitochondrial respiratory chain
… gehört ebenso wie Plasmodium falciparum zu den Apicomplexa. Das in den letzten Jahren gehäufte Auftreten von Resistenzen gegenüber gängigen Therapeutika macht die Erforschung neuer medikamentöser Angriffspunkte für diese Parasiten notwendig. Die mitochondriale Atmungskette von Toxoplasmen und …
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Transcriptional regulation in Plasmodium falciparum: characterisation of TBP-like protein
… the prevalence of disordered regions within Apicomplexan TLPs, (ii) an investigation into the role of these regions in PfTLP DNA binding and (iii) an in-depth characterisation of phase separation by PfTLP IDRs and full-length PfTLP. This study highlights the prevalence of TLPs within …
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Neospora caninum - eine Abortursache beim Rind
… that N. caninum belongs to the phylum of Apicomplexa, the class of Sporozoa, the subclass of Coccidia, the order of Eucoccidia and the suborder of Eimeriina. During its life cycle N. caninum passes through various phases like sporogony, schizogony and gamogony. Definitive and intermediate …
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Prevalence and Identity of Tissue Cyst Forming Apicomplexan Parasites in the Muscles of Raptors
… information on the distribution and diversity of Apicomplexan protozoal infections in the tissues of raptors in the United States. Protozoan encephalitis caused by Sarcocystis species and Toxoplasma gondii is being increasingly reported in raptors from various locations in the United States. To …